Abstract
The authors report the case of a 15-year-old girl suffering from Lafora's disease, confirmed by skin biopsy performed according to the Carpenter-Karpati technique. Elementary partial seizures characterized the beginning of the disease, whereas generalized convulsive seizures and myoclonic jerks appeared later. Lastly, frequent epileptic states occurred. Since a dopaminergic mechanism seems to be involved in the pathophysiology of photosensitive epilepsy, bromocriptine and successively selegiline were added to the standard antiepileptic treatment. The dopaminergic agonist and the B-MAO inhibitor markedly reduced the seizure frequency, increasing vigilance and responsiveness. This effect was more evident during the treatment with both drugs.
| Translated title of the contribution | Dopaminergic treatment in a case of Lafora's disease |
|---|---|
| Original language | Italian |
| Pages (from-to) | 63-65 |
| Number of pages | 3 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Volume | No. 54-55 |
| Publication status | Published - 1986 |
ASJC Scopus subject areas
- Clinical Neurology