Abstract
The authors report the case of a 15-year-old girl suffering from Lafora's disease, confirmed by skin biopsy performed according to the Carpenter-Karpati technique. Elementary partial seizures characterized the beginning of the disease, whereas generalized convulsive seizures and myoclonic jerks appeared later. Lastly, frequent epileptic states occurred. Since a dopaminergic mechanism seems to be involved in the pathophysiology of photosensitive epilepsy, bromocriptine and successively selegiline were added to the standard antiepileptic treatment. The dopaminergic agonist and the B-MAO inhibitor markedly reduced the seizure frequency, increasing vigilance and responsiveness. This effect was more evident during the treatment with both drugs.
| Original language | Italian |
|---|---|
| Pages (from-to) | 63-65 |
| Number of pages | 3 |
| Journal | Bollettino - Lega Italiana contro l'Epilessia |
| Volume | No. 54-55 |
| Publication status | Published - 1986 |
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ASJC Scopus subject areas
- Clinical Neurology
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TRATTAMENTO CON AGONISTI DOPAMINERGICI IN CORSO DI MALATTIA DI LAFORA. / Mauro, A. M.; Scarpino, O.; Pelliccioni, G.
In: Bollettino - Lega Italiana contro l'Epilessia, Vol. No. 54-55, 1986, p. 63-65.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - TRATTAMENTO CON AGONISTI DOPAMINERGICI IN CORSO DI MALATTIA DI LAFORA
AU - Mauro, A. M.
AU - Scarpino, O.
AU - Pelliccioni, G.
PY - 1986
Y1 - 1986
N2 - The authors report the case of a 15-year-old girl suffering from Lafora's disease, confirmed by skin biopsy performed according to the Carpenter-Karpati technique. Elementary partial seizures characterized the beginning of the disease, whereas generalized convulsive seizures and myoclonic jerks appeared later. Lastly, frequent epileptic states occurred. Since a dopaminergic mechanism seems to be involved in the pathophysiology of photosensitive epilepsy, bromocriptine and successively selegiline were added to the standard antiepileptic treatment. The dopaminergic agonist and the B-MAO inhibitor markedly reduced the seizure frequency, increasing vigilance and responsiveness. This effect was more evident during the treatment with both drugs.
AB - The authors report the case of a 15-year-old girl suffering from Lafora's disease, confirmed by skin biopsy performed according to the Carpenter-Karpati technique. Elementary partial seizures characterized the beginning of the disease, whereas generalized convulsive seizures and myoclonic jerks appeared later. Lastly, frequent epileptic states occurred. Since a dopaminergic mechanism seems to be involved in the pathophysiology of photosensitive epilepsy, bromocriptine and successively selegiline were added to the standard antiepileptic treatment. The dopaminergic agonist and the B-MAO inhibitor markedly reduced the seizure frequency, increasing vigilance and responsiveness. This effect was more evident during the treatment with both drugs.
UR - http://www.scopus.com/inward/record.url?scp=0022976384&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022976384&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0022976384
VL - No. 54-55
SP - 63
EP - 65
JO - Bollettino - Lega Italiana contro l'Epilessia
JF - Bollettino - Lega Italiana contro l'Epilessia
SN - 0394-560X
ER -