TRATTAMENTO CON AGONISTI DOPAMINERGICI IN CORSO DI MALATTIA DI LAFORA

Translated title of the contribution: Dopaminergic treatment in a case of Lafora's disease

A. M. Mauro, O. Scarpino, G. Pelliccioni

Research output: Contribution to journalArticlepeer-review

Abstract

The authors report the case of a 15-year-old girl suffering from Lafora's disease, confirmed by skin biopsy performed according to the Carpenter-Karpati technique. Elementary partial seizures characterized the beginning of the disease, whereas generalized convulsive seizures and myoclonic jerks appeared later. Lastly, frequent epileptic states occurred. Since a dopaminergic mechanism seems to be involved in the pathophysiology of photosensitive epilepsy, bromocriptine and successively selegiline were added to the standard antiepileptic treatment. The dopaminergic agonist and the B-MAO inhibitor markedly reduced the seizure frequency, increasing vigilance and responsiveness. This effect was more evident during the treatment with both drugs.

Translated title of the contributionDopaminergic treatment in a case of Lafora's disease
Original languageItalian
Pages (from-to)63-65
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
VolumeNo. 54-55
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Clinical Neurology

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