Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico.

Translated title of the contribution: Doppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus

E. Astorri, P. Fiorina, E. Ridolo, G. A. Contini, D. Albertini, P. Dall'Aglio

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This study was aimed at investigating abnormalities in left ventricular size and function in patients with systemic lupus erythematosus without overt cardiovascular manifestations, in order to detect a very early impairment in myocardial function. Seventeen females and 1 male with systemic lupus erythematosus of 4 to 20 year duration and without clinical evidence of heart disease were studied. Twelve healthy volunteers, matched for age, sex and quatelet index, were utilized as controls. Each patient had a two-dimensional M-mode echocardiographic and Doppler examination. In patients with systemic lupus erythematosus there was an increase in left ventricular ejection fraction (p <0.001), a slight reduction of end-diastolic volume index and a significant decrease of end-systolic volume index (p <0.001). In the same patients we also found prolongation of the isovolumic relaxation time (p <0.02), a clear impairment of diastolic filling parameters. Peak E velocity was lower (p <0.01), peak A velocity was higher (p <0.01), with a clear lowering, of the corresponding E/A ratio (p <0.001) in patients with systemic lupus erythematosus.

Original languageItalian
Pages (from-to)1179-1183
Number of pages5
JournalCardiologia
Volume42
Issue number11
Publication statusPublished - Nov 1997

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Left Ventricular Function
Systemic Lupus Erythematosus
Stroke Volume
Heart Diseases
Healthy Volunteers

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Astorri, E., Fiorina, P., Ridolo, E., Contini, G. A., Albertini, D., & Dall'Aglio, P. (1997). Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico. Cardiologia, 42(11), 1179-1183.

Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico. / Astorri, E.; Fiorina, P.; Ridolo, E.; Contini, G. A.; Albertini, D.; Dall'Aglio, P.

In: Cardiologia, Vol. 42, No. 11, 11.1997, p. 1179-1183.

Research output: Contribution to journalArticle

Astorri, E, Fiorina, P, Ridolo, E, Contini, GA, Albertini, D & Dall'Aglio, P 1997, 'Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico.', Cardiologia, vol. 42, no. 11, pp. 1179-1183.
Astorri E, Fiorina P, Ridolo E, Contini GA, Albertini D, Dall'Aglio P. Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico. Cardiologia. 1997 Nov;42(11):1179-1183.
Astorri, E. ; Fiorina, P. ; Ridolo, E. ; Contini, G. A. ; Albertini, D. ; Dall'Aglio, P. / Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico. In: Cardiologia. 1997 ; Vol. 42, No. 11. pp. 1179-1183.
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