Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico.

Translated title of the contribution: Doppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus

E. Astorri, P. Fiorina, E. Ridolo, G. A. Contini, D. Albertini, P. Dall'Aglio

Research output: Contribution to journalArticlepeer-review

Abstract

This study was aimed at investigating abnormalities in left ventricular size and function in patients with systemic lupus erythematosus without overt cardiovascular manifestations, in order to detect a very early impairment in myocardial function. Seventeen females and 1 male with systemic lupus erythematosus of 4 to 20 year duration and without clinical evidence of heart disease were studied. Twelve healthy volunteers, matched for age, sex and quatelet index, were utilized as controls. Each patient had a two-dimensional M-mode echocardiographic and Doppler examination. In patients with systemic lupus erythematosus there was an increase in left ventricular ejection fraction (p <0.001), a slight reduction of end-diastolic volume index and a significant decrease of end-systolic volume index (p <0.001). In the same patients we also found prolongation of the isovolumic relaxation time (p <0.02), a clear impairment of diastolic filling parameters. Peak E velocity was lower (p <0.01), peak A velocity was higher (p <0.01), with a clear lowering, of the corresponding E/A ratio (p <0.001) in patients with systemic lupus erythematosus.

Translated title of the contributionDoppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus
Original languageItalian
Pages (from-to)1179-1183
Number of pages5
JournalCardiologia
Volume42
Issue number11
Publication statusPublished - Nov 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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