Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico.

Translated title of the contribution: Doppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus

E. Astorri, P. Fiorina, E. Ridolo, G. A. Contini, D. Albertini, P. Dall'Aglio

Research output: Contribution to journalArticle

Abstract

This study was aimed at investigating abnormalities in left ventricular size and function in patients with systemic lupus erythematosus without overt cardiovascular manifestations, in order to detect a very early impairment in myocardial function. Seventeen females and 1 male with systemic lupus erythematosus of 4 to 20 year duration and without clinical evidence of heart disease were studied. Twelve healthy volunteers, matched for age, sex and quatelet index, were utilized as controls. Each patient had a two-dimensional M-mode echocardiographic and Doppler examination. In patients with systemic lupus erythematosus there was an increase in left ventricular ejection fraction (p <0.001), a slight reduction of end-diastolic volume index and a significant decrease of end-systolic volume index (p <0.001). In the same patients we also found prolongation of the isovolumic relaxation time (p <0.02), a clear impairment of diastolic filling parameters. Peak E velocity was lower (p <0.01), peak A velocity was higher (p <0.01), with a clear lowering, of the corresponding E/A ratio (p <0.001) in patients with systemic lupus erythematosus.

Translated title of the contributionDoppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus
Original languageItalian
Pages (from-to)1179-1183
Number of pages5
JournalCardiologia
Volume42
Issue number11
Publication statusPublished - Nov 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Doppler echocardiographic study of left ventricular function in patients with systemic lupus erythematosus'. Together they form a unique fingerprint.

  • Cite this

    Astorri, E., Fiorina, P., Ridolo, E., Contini, G. A., Albertini, D., & Dall'Aglio, P. (1997). Studio ecocardiografico Doppler della funzione ventricolare sinistra in pazienti con lupus eritematoso sistemico. Cardiologia, 42(11), 1179-1183.