Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy

Antonella Fogliata; Marta Scorsetti; Piera Navarria; Maddalena Catalano; Alessandro Clivio; Luca Cozzi; Francesca Lobefalo; Giorgia Nicolini; Valentina Palumbo; Chiara Pellegrini; Giacomo Reggiori; Antonella Roggio; Eugenio Vanetti; Filippo Alongi; Sara Pentimalli; Pietro Mancosu

doi:10.3109/0284186X.2012.689853

Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy

Antonella Fogliata, Marta Scorsetti, Piera Navarria, Maddalena Catalano, Alessandro Clivio, Luca Cozzi, Francesca Lobefalo, Giorgia Nicolini, Valentina Palumbo, Chiara Pellegrini, Giacomo Reggiori, Antonella Roggio, Eugenio Vanetti, Filippo Alongi, Sara Pentimalli, Pietro Mancosu

Research output: Contribution to journal › Article › peer-review

Abstract

Background. To appraise the potential of volumetric modulated arc therapy (VMAT, RapidArc) and proton beams to simultaneously achieve target coverage and enhanced sparing of bone tissue in the treatment of soft-tissue sarcoma with adequate target coverage. Material and methods. Ten patients presenting with soft-tissue sarcoma of the leg were collected for the study. Dose was prescribed to 66.5 Gy in 25 fractions to the planning target volume (PTV) while significant maximum dose to the bone was constrained to 50 Gy. Plans were optimised according to the RapidArc technique with 6 MV photon beams or for intensity modulated protons. RapidArc photon plans were computed with: 1) AAA; 2) Acuros XB as dose to medium; and 3) Acuros XB as dose to water. Results. All plans acceptably met the criteria of target coverage (V95% >90-95%) and bone sparing (D1cm3

Original language	English
Pages (from-to)	545-552
Number of pages	8
Journal	Acta Oncologica
Volume	52
Issue number	3
DOIs	https://doi.org/10.3109/0284186X.2012.689853
Publication status	Published - Apr 2013

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Hematology

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Fogliata, A., Scorsetti, M., Navarria, P., Catalano, M., Clivio, A., Cozzi, L., Lobefalo, F., Nicolini, G., Palumbo, V., Pellegrini, C., Reggiori, G., Roggio, A., Vanetti, E., Alongi, F., Pentimalli, S., & Mancosu, P. (2013). Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy. Acta Oncologica, 52(3), 545-552. https://doi.org/10.3109/0284186X.2012.689853

Fogliata, A, Scorsetti, M , Navarria, P, Catalano, M, Clivio, A, Cozzi, L, Lobefalo, F, Nicolini, G, Palumbo, V, Pellegrini, C, Reggiori, G, Roggio, A, Vanetti, E, Alongi, F, Pentimalli, S & Mancosu, P 2013, 'Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy', Acta Oncologica, vol. 52, no. 3, pp. 545-552. https://doi.org/10.3109/0284186X.2012.689853

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abstract = "Background. To appraise the potential of volumetric modulated arc therapy (VMAT, RapidArc) and proton beams to simultaneously achieve target coverage and enhanced sparing of bone tissue in the treatment of soft-tissue sarcoma with adequate target coverage. Material and methods. Ten patients presenting with soft-tissue sarcoma of the leg were collected for the study. Dose was prescribed to 66.5 Gy in 25 fractions to the planning target volume (PTV) while significant maximum dose to the bone was constrained to 50 Gy. Plans were optimised according to the RapidArc technique with 6 MV photon beams or for intensity modulated protons. RapidArc photon plans were computed with: 1) AAA; 2) Acuros XB as dose to medium; and 3) Acuros XB as dose to water. Results. All plans acceptably met the criteria of target coverage (V95% >90-95%) and bone sparing (D1cm3 ",

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AU - Fogliata, Antonella

AU - Scorsetti, Marta

AU - Navarria, Piera

AU - Catalano, Maddalena

AU - Clivio, Alessandro

AU - Cozzi, Luca

AU - Lobefalo, Francesca

AU - Nicolini, Giorgia

AU - Palumbo, Valentina

AU - Pellegrini, Chiara

AU - Reggiori, Giacomo

AU - Roggio, Antonella

AU - Vanetti, Eugenio

AU - Alongi, Filippo

AU - Pentimalli, Sara

AU - Mancosu, Pietro

PY - 2013/4

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N2 - Background. To appraise the potential of volumetric modulated arc therapy (VMAT, RapidArc) and proton beams to simultaneously achieve target coverage and enhanced sparing of bone tissue in the treatment of soft-tissue sarcoma with adequate target coverage. Material and methods. Ten patients presenting with soft-tissue sarcoma of the leg were collected for the study. Dose was prescribed to 66.5 Gy in 25 fractions to the planning target volume (PTV) while significant maximum dose to the bone was constrained to 50 Gy. Plans were optimised according to the RapidArc technique with 6 MV photon beams or for intensity modulated protons. RapidArc photon plans were computed with: 1) AAA; 2) Acuros XB as dose to medium; and 3) Acuros XB as dose to water. Results. All plans acceptably met the criteria of target coverage (V95% >90-95%) and bone sparing (D1cm3

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Dosimetric comparison between VMAT with different dose calculation algorithms and protons for soft-tissue sarcoma radiotherapy

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