In this double-blind clinical trial we compared the prophylactic efficacy of the calcium-entry blocker flunarizine (15 mg nocte) with that of pizotifen (1.5 mg nocte) in 30 patients affected by classical and common migraine. During a two months treatment both drugs showed a good efficacy. Flunarizine tended to more markedly suppress severity of pain and duration of attacks than pizotifen. Daytime drowsiness and weight gain occurred with both drugs; the first side effect was more evident in the group treated with flunarizine, the second one in the group treated with pizotifen.
|Translated title of the contribution||Double-blind clinical trial of flunarizine against pizotifen in a single evening dose in patients with migraine|
|Number of pages||8|
|Journal||Rivista di Neurologia|
|Publication status||Published - 1985|
ASJC Scopus subject areas
- Clinical Neurology