STUDIO CLINICO IN DOPPIO CIECO: FLUNARIZINA CONTRO PIZOTIFENE IN UN'UNICA SOMMINISTRAZIONE SERALE IN PAZIENTI EMICRANICI

Translated title of the contribution: Double-blind clinical trial of flunarizine against pizotifen in a single evening dose in patients with migraine

R. Cerbo, M. Casacchia, R. Formisano, M. G. Buzzi, B. Boni, M. Feliciani, G. Grillo, G. Cusimano, A. Agnoli

Research output: Contribution to journalArticlepeer-review

Abstract

In this double-blind clinical trial we compared the prophylactic efficacy of the calcium-entry blocker flunarizine (15 mg nocte) with that of pizotifen (1.5 mg nocte) in 30 patients affected by classical and common migraine. During a two months treatment both drugs showed a good efficacy. Flunarizine tended to more markedly suppress severity of pain and duration of attacks than pizotifen. Daytime drowsiness and weight gain occurred with both drugs; the first side effect was more evident in the group treated with flunarizine, the second one in the group treated with pizotifen.

Translated title of the contributionDouble-blind clinical trial of flunarizine against pizotifen in a single evening dose in patients with migraine
Original languageItalian
Pages (from-to)139-146
Number of pages8
JournalRivista di Neurologia
Volume55
Issue number2
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Clinical Neurology

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