DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

M. Del Re; S. Cinieri; A. Michelucci; S. Salvadori; F. Loupakis; M. Schirripa; C. Cremolini; S. Crucitta; C. Barbara; A. Di Leo; T.P. Latiano; F. Pietrantonio; S. Di Donato; P. Simi; A. Passardi; F. De Braud; G. Altavilla; C. Zamagni; R. Bordonaro; A. Butera; E. Maiello; C. Pinto; A. Falcone; V. Mazzotti; R. Morganti; R. Danesi

doi:10.1038/s41397-019-0077-1

DPYD6 plays an important role in fluoropyrimidine toxicity in addition to DPYD2A and c.2846A>T: a comprehensive analysis in 1254 patients

M. Del Re, S. Cinieri, A. Michelucci, S. Salvadori, F. Loupakis, M. Schirripa, C. Cremolini, S. Crucitta, C. Barbara, A. Di Leo, T.P. Latiano, F. Pietrantonio, S. Di Donato, P. Simi, A. Passardi, F. De Braud, G. Altavilla, C. Zamagni, R. Bordonaro, A. ButeraE. Maiello, C. Pinto, A. Falcone, V. Mazzotti, R. Morganti, R. Danesi

Research output: Contribution to journal › Article

Original language	Italian
Pages (from-to)	556-563
Number of pages	8
Journal	Pharmacogenomics Journal
Volume	19
Issue number	6
DOIs	https://doi.org/10.1038/s41397-019-0077-1
Publication status	Published - 2019

Cite this

Del Re, M., Cinieri, S., Michelucci, A., Salvadori, S., Loupakis, F., Schirripa, M., ... Danesi, R. (2019). DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients. Pharmacogenomics Journal, 19(6), 556-563. https://doi.org/10.1038/s41397-019-0077-1

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients. / Del Re, M.; Cinieri, S.; Michelucci, A.; Salvadori, S.; Loupakis, F.; Schirripa, M.; Cremolini, C.; Crucitta, S.; Barbara, C.; Di Leo, A.; Latiano, T.P.; Pietrantonio, F.; Di Donato, S.; Simi, P.; Passardi, A.; De Braud, F.; Altavilla, G.; Zamagni, C.; Bordonaro, R.; Butera, A.; Maiello, E.; Pinto, C.; Falcone, A.; Mazzotti, V.; Morganti, R.; Danesi, R.

In: Pharmacogenomics Journal, Vol. 19, No. 6, 2019, p. 556-563.

Research output: Contribution to journal › Article

Del Re, M, Cinieri, S, Michelucci, A, Salvadori, S, Loupakis, F , Schirripa, M, Cremolini, C, Crucitta, S, Barbara, C, Di Leo, A, Latiano, TP, Pietrantonio, F, Di Donato, S, Simi, P, Passardi, A , De Braud, F, Altavilla, G, Zamagni, C, Bordonaro, R, Butera, A , Maiello, E , Pinto, C , Falcone, A, Mazzotti, V, Morganti, R & Danesi, R 2019, 'DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients', Pharmacogenomics Journal, vol. 19, no. 6, pp. 556-563. https://doi.org/10.1038/s41397-019-0077-1

Del Re, M. ; Cinieri, S. ; Michelucci, A. ; Salvadori, S. ; Loupakis, F. ; Schirripa, M. ; Cremolini, C. ; Crucitta, S. ; Barbara, C. ; Di Leo, A. ; Latiano, T.P. ; Pietrantonio, F. ; Di Donato, S. ; Simi, P. ; Passardi, A. ; De Braud, F. ; Altavilla, G. ; Zamagni, C. ; Bordonaro, R. ; Butera, A. ; Maiello, E. ; Pinto, C. ; Falcone, A. ; Mazzotti, V. ; Morganti, R. ; Danesi, R. / DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients. In: Pharmacogenomics Journal. 2019 ; Vol. 19, No. 6. pp. 556-563.

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title = "DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients",

author = "{Del Re}, M. and S. Cinieri and A. Michelucci and S. Salvadori and F. Loupakis and M. Schirripa and C. Cremolini and S. Crucitta and C. Barbara and {Di Leo}, A. and T.P. Latiano and F. Pietrantonio and {Di Donato}, S. and P. Simi and A. Passardi and {De Braud}, F. and G. Altavilla and C. Zamagni and R. Bordonaro and A. Butera and E. Maiello and C. Pinto and A. Falcone and V. Mazzotti and R. Morganti and R. Danesi",

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T1 - DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

AU - Del Re, M.

AU - Cinieri, S.

AU - Michelucci, A.

AU - Salvadori, S.

AU - Loupakis, F.

AU - Schirripa, M.

AU - Cremolini, C.

AU - Crucitta, S.

AU - Barbara, C.

AU - Di Leo, A.

AU - Latiano, T.P.

AU - Pietrantonio, F.

AU - Di Donato, S.

AU - Simi, P.

AU - Passardi, A.

AU - De Braud, F.

AU - Altavilla, G.

AU - Zamagni, C.

AU - Bordonaro, R.

AU - Butera, A.

AU - Maiello, E.

AU - Pinto, C.

AU - Falcone, A.

AU - Mazzotti, V.

AU - Morganti, R.

AU - Danesi, R.

N1 - Cited By :1 Export Date: 25 February 2020

PY - 2019

Y1 - 2019

U2 - 10.1038/s41397-019-0077-1

DO - 10.1038/s41397-019-0077-1

M3 - Articolo

VL - 19

SP - 556

EP - 563

JO - Pharmacogenomics Journal

JF - Pharmacogenomics Journal

SN - 1470-269X

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Access to Document

10.1038/s41397-019-0077-1

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061214493&doi=10.1038%2fs41397-019-0077-1&partnerID=40&md5=27a16cc991ac8c8a122a4e0fd36aad68

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Istituto Scientifico Romagnolo - MEDICINA DI PRECISIONE, GENERE, ETNIA E "GEROSCIENCE": MECCANISMI GENETICO- MOLECOLARI NELLO SVILUPPO, CARATTERIZZAZIONE E TERAPIA DEI TUMORI