Dramatic response to levetiracetam in post-ischaemic Holmes' tremor

P. Striano, Andrea Elefante, Antonietta Coppola, Fabio Tortora, Federico Zara, Carlo Minetti

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Holmes' tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes' tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes' tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes' tremor dramatically responded to levetiracetam treatment.

Original languageEnglish
JournalBMJ Case Reports
DOIs
Publication statusPublished - Jan 23 2009

Fingerprint

etiracetam
Tremor
Clonazepam
Dopamine Agents
Vascular Malformations
Arteriosclerosis
Levodopa
Thalamus
Propranolol
Cerebellum
Brain Stem
Multiple Sclerosis
Extremities
Stroke

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dramatic response to levetiracetam in post-ischaemic Holmes' tremor. / Striano, P.; Elefante, Andrea; Coppola, Antonietta; Tortora, Fabio; Zara, Federico; Minetti, Carlo.

In: BMJ Case Reports, 23.01.2009.

Research output: Contribution to journalArticle

@article{667a630f733e4a5194cdbe2cf8e8d612,
title = "Dramatic response to levetiracetam in post-ischaemic Holmes' tremor",
abstract = "Holmes' tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes' tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes' tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes' tremor dramatically responded to levetiracetam treatment.",
author = "P. Striano and Andrea Elefante and Antonietta Coppola and Fabio Tortora and Federico Zara and Carlo Minetti",
year = "2009",
month = "1",
day = "23",
doi = "10.1136/bcr.08.2008.0643",
language = "English",
journal = "BMJ Case Reports",
issn = "1757-790X",
publisher = "BRITISH INST RADIOLOGY",

}

TY - JOUR

T1 - Dramatic response to levetiracetam in post-ischaemic Holmes' tremor

AU - Striano, P.

AU - Elefante, Andrea

AU - Coppola, Antonietta

AU - Tortora, Fabio

AU - Zara, Federico

AU - Minetti, Carlo

PY - 2009/1/23

Y1 - 2009/1/23

N2 - Holmes' tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes' tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes' tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes' tremor dramatically responded to levetiracetam treatment.

AB - Holmes' tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes' tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes' tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes' tremor dramatically responded to levetiracetam treatment.

UR - http://www.scopus.com/inward/record.url?scp=84897585674&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897585674&partnerID=8YFLogxK

U2 - 10.1136/bcr.08.2008.0643

DO - 10.1136/bcr.08.2008.0643

M3 - Article

JO - BMJ Case Reports

JF - BMJ Case Reports

SN - 1757-790X

ER -