TY - JOUR
T1 - Drawing lines and circles in Parkinson's Disease
T2 - The lateralized symptoms interfere with the movements of the unaffected hand
AU - Scarpina, Federica
AU - Bruno, Valentina
AU - Rabuffetti, Marco
AU - Priano, Lorenzo
AU - Tagini, Sofia
AU - Gindri, Patrizia
AU - Mauro, Alessandro
AU - Garbarini, Francesca
N1 - Funding Information:
This work has been funded by the MIUR- SIR 2014 grant ( RBSI146V1D ) and by the San Paolo Foundation grant ( CSTO165140 ) to F.G. This study was supported by Ministero dell'Istruzione, dell'Università e della Ricerca – MIUR , project “Dipartimenti di Eccellenza 2018–2022″ to Dept. of Neuroscience “Rita Levi Montalcini”, University of Turin , Italy. The authors have received no further funding from other institutions, including personal relationships, interests, grants, employment, affiliations, patents, inventions, honoraria, consultancies, royalties, stock options/ownership, or expert testimony for the last 12 months.
Publisher Copyright:
© 2020 Elsevier Ltd
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/1
Y1 - 2021/1
N2 - Introduction: Evidence about altered bimanual coordination has been reported in Parkinson's Disease. However, no previous study has explored such an alteration quantifying the interference effect that the trajectory of each hand might impose on the other one. Thus, in the present research, we applied the traditional Circles-Lines Coupling Task, which allowed assessing the motor coordination of the two hands, in the context of Parkinson's Disease. Methods: Thirty-six individuals affected by Parkinson's Disease were consecutively recruited and assigned to two groups according to their symptoms' lateralization. Moreover, eighteen age-matched healthy controls participated in the study. We capitalized on the Circles-Lines Coupling Task, in which the performance during incongruent movements (drawing lines with one hand and circles with the other hand) was compared with the performance during congruent movements (drawing lines with both hands). A bimanual coupling index was computed to compare the interference effect of each hand on the other one. Results: In healthy controls, the bimanual coupling index did not differ between the two hands. Crucially, in both groups of individuals affected by Parkinson's Disease, the less affected hand showed a significantly higher bimanual coupling index, due to the abnormal interference exerted by the most affected one, than vice versa. Conclusions: Our results highlighted an altered spatial bimanual coupling in Parkinson's disease, depending on the symptoms' lateralization. We offered different explanations of our results according to the theoretical frameworks about the mechanisms subserving bimanual coordination.
AB - Introduction: Evidence about altered bimanual coordination has been reported in Parkinson's Disease. However, no previous study has explored such an alteration quantifying the interference effect that the trajectory of each hand might impose on the other one. Thus, in the present research, we applied the traditional Circles-Lines Coupling Task, which allowed assessing the motor coordination of the two hands, in the context of Parkinson's Disease. Methods: Thirty-six individuals affected by Parkinson's Disease were consecutively recruited and assigned to two groups according to their symptoms' lateralization. Moreover, eighteen age-matched healthy controls participated in the study. We capitalized on the Circles-Lines Coupling Task, in which the performance during incongruent movements (drawing lines with one hand and circles with the other hand) was compared with the performance during congruent movements (drawing lines with both hands). A bimanual coupling index was computed to compare the interference effect of each hand on the other one. Results: In healthy controls, the bimanual coupling index did not differ between the two hands. Crucially, in both groups of individuals affected by Parkinson's Disease, the less affected hand showed a significantly higher bimanual coupling index, due to the abnormal interference exerted by the most affected one, than vice versa. Conclusions: Our results highlighted an altered spatial bimanual coupling in Parkinson's disease, depending on the symptoms' lateralization. We offered different explanations of our results according to the theoretical frameworks about the mechanisms subserving bimanual coordination.
KW - Action monitoring
KW - Bimanual coupling
KW - Interlimb coordination
KW - Motor intention
KW - Parkinson's disease
UR - http://www.scopus.com/inward/record.url?scp=85098602250&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098602250&partnerID=8YFLogxK
U2 - 10.1016/j.neuropsychologia.2020.107718
DO - 10.1016/j.neuropsychologia.2020.107718
M3 - Article
C2 - 33309678
AN - SCOPUS:85098602250
VL - 151
JO - Neuropsychologia
JF - Neuropsychologia
SN - 0028-3932
M1 - 107718
ER -