Driving habits and risk factors for traffic accidents among sleep apnea patients - a European multi-centre cohort study

Mahssa Karimi, Jan Hedner, Carolina Lombardi, Walter T. Mcnicholas, Thomas Penzel, Renata L. Riha, Daniel Rodenstein, Ludger Grote, F. Barbé, O. Basoglu, P. Bielicki, M. Bonsignore, P. Escourrou, L. Grote, J. Hedner, J. F M Jiménez, J. A. Kvamme, P. Levy, C. Lombardi, J. F. MasaO. Marrone, J. M. Montserrat, W. T. McNicholas, A. Pataka, T. Penzel, G. Parati, J. L. Pepin, M. Pretl, R. L. Riha, D. Rodenstein, R. Schulz, T. Saaresranta, P. Sliwinski, R. Staats, P. Steiropoulos, R. Tkacova, P. J. Safarik, G. Varoneckas, A. Vitols, J. Verbraecken

Research output: Contribution to journalArticlepeer-review


Obstructive sleep apnea is associated with increased motor vehicle accident risk, and improved detection of patients at risk is of importance. The present study addresses potential risk factors in the European Sleep Apnea Database and includes patients with suspected obstructive sleep apnea [n = 8476, age 51.5 (12.5) years, body mass index 31.0 (6.6) kg m-2, 82.4% driver's licence holders]. Driving distance (km year-1), driver's licence type, sleep apnea severity, sleepiness and comorbidities were assessed. Previously validated risk factors for accident history: Epworth Sleepiness Scale ≥16; habitual sleep time ≤5 h; use of hypnotics; and driving ≥15 000 km year-1 were analysed across European regions. At least one risk factor was identified in male and female drivers, 68.75 and 51.3%, respectively. The occurrence of the risk factors was similar across Europe, with only a lower rate in the eastern region (P = 0.001). The mean number of risk factors increased across classes of sleep apnea severity. Frequent driving was prevalent [14.0 (interquartile range 8.0-20.0) × 103 km year-1] and 32.7% of drivers had severe obstructive sleep apnea [apnea-hypopnea index 50.3 (38.8-66.0) n h-1]. Obesity, shorter sleep time and younger age were associated with increased traffic exposure (P ≤ 0.03). In conclusion, the risk factors associated with accident history were common among European patients with suspected obstructive sleep apnea, but varied between geographical regions. There was a weak covariation between occurrence of risk factors and clinically determined apnea severity but frequent driving, a strong risk factor for accidents, was over-represented. Systematic evaluation of accident-related risk factors is important to detect sleep apnea patients at risk for motor vehicle accidents.

Original languageEnglish
Pages (from-to)689-699
Number of pages11
JournalJournal of Sleep Research
Issue number6
Publication statusPublished - Dec 1 2014


  • Driving exposure
  • Hypersomnia
  • Motor vehicle crash
  • Registry
  • Sleepy driving
  • Traffic risk

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Medicine(all)


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