Drug-eluting stents vs. bare metal stents in saphenous vein graft disease: Insights from a meta-analysis of 7,090 patients

Alessandro Lupi; Eliano Pio Navarese; Maurizio Lazzero; Mara Sansa; Stefano De Servi; Antonio Serra; Angelo Sante Bongo; Antonio Buffon

doi:10.1253/circj.CJ-10-0186

Drug-eluting stents vs. bare metal stents in saphenous vein graft disease: Insights from a meta-analysis of 7,090 patients

Alessandro Lupi, Eliano Pio Navarese, Maurizio Lazzero, Mara Sansa, Stefano De Servi, Antonio Serra, Angelo Sante Bongo, Antonio Buffon

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Evidence supporting the use of drug-eluting stents (DES) in saphenous vein graft (SVG) disease is uncertain. Previous studies have suggested that DES might reduce the re-intervention rate in SVG disease, with conflicting data on mortality. Thus, a meta-analysis was performed to compare outcomes of DES vs. bare metal stent (BMS) in SVG disease. Methods and Results: Medline and Web databases were searched for studies comparing DES and BMS for SVG disease, reporting rates of overall mortality, target vessel revascularization (TVR) and myocardial infarction (MI) with a follow-up of ≥6 months. The meta-analysis included 23 studies (7,090 patients). Compared with BMS, DES-treated patients had lower rates of TVR (odds ratio (OR), 0.53; confidence interval (CI), 0.39-0.72; P

Original language	English
Pages (from-to)	280-289
Number of pages	10
Journal	Circulation Journal
Volume	75
Issue number	2
DOIs	https://doi.org/10.1253/circj.CJ-10-0186
Publication status	Published - Feb 2011

Keywords

Angioplasty
Coronary artery bypass grafting
Drug-eluting stents
Meta-analysis
Stents

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1253/circj.CJ-10-0186

Fingerprint Dive into the research topics of 'Drug-eluting stents vs. bare metal stents in saphenous vein graft disease: Insights from a meta-analysis of 7,090 patients'. Together they form a unique fingerprint.

Cite this

Drug-eluting stents vs. bare metal stents in saphenous vein graft disease : Insights from a meta-analysis of 7,090 patients. / Lupi, Alessandro; Navarese, Eliano Pio; Lazzero, Maurizio; Sansa, Mara; De Servi, Stefano; Serra, Antonio; Bongo, Angelo Sante; Buffon, Antonio.

In: Circulation Journal, Vol. 75, No. 2, 02.2011, p. 280-289.

Research output: Contribution to journal › Article › peer-review

@article{3f548763cd4c4d20a9eef057e70dd45e,

title = "Drug-eluting stents vs. bare metal stents in saphenous vein graft disease: Insights from a meta-analysis of 7,090 patients",

abstract = "Background: Evidence supporting the use of drug-eluting stents (DES) in saphenous vein graft (SVG) disease is uncertain. Previous studies have suggested that DES might reduce the re-intervention rate in SVG disease, with conflicting data on mortality. Thus, a meta-analysis was performed to compare outcomes of DES vs. bare metal stent (BMS) in SVG disease. Methods and Results: Medline and Web databases were searched for studies comparing DES and BMS for SVG disease, reporting rates of overall mortality, target vessel revascularization (TVR) and myocardial infarction (MI) with a follow-up of ≥6 months. The meta-analysis included 23 studies (7,090 patients). Compared with BMS, DES-treated patients had lower rates of TVR (odds ratio (OR), 0.53; confidence interval (CI), 0.39-0.72; P",

keywords = "Angioplasty, Coronary artery bypass grafting, Drug-eluting stents, Meta-analysis, Stents",

author = "Alessandro Lupi and Navarese, {Eliano Pio} and Maurizio Lazzero and Mara Sansa and {De Servi}, Stefano and Antonio Serra and Bongo, {Angelo Sante} and Antonio Buffon",

year = "2011",

month = feb,

doi = "10.1253/circj.CJ-10-0186",

language = "English",

volume = "75",

pages = "280--289",

journal = "Circulation Journal",

issn = "1346-9843",

publisher = "Japanese Circulation Society",

number = "2",

}

TY - JOUR

T1 - Drug-eluting stents vs. bare metal stents in saphenous vein graft disease

T2 - Insights from a meta-analysis of 7,090 patients

AU - Lupi, Alessandro

AU - Navarese, Eliano Pio

AU - Lazzero, Maurizio

AU - Sansa, Mara

AU - De Servi, Stefano

AU - Serra, Antonio

AU - Bongo, Angelo Sante

AU - Buffon, Antonio

PY - 2011/2

Y1 - 2011/2

N2 - Background: Evidence supporting the use of drug-eluting stents (DES) in saphenous vein graft (SVG) disease is uncertain. Previous studies have suggested that DES might reduce the re-intervention rate in SVG disease, with conflicting data on mortality. Thus, a meta-analysis was performed to compare outcomes of DES vs. bare metal stent (BMS) in SVG disease. Methods and Results: Medline and Web databases were searched for studies comparing DES and BMS for SVG disease, reporting rates of overall mortality, target vessel revascularization (TVR) and myocardial infarction (MI) with a follow-up of ≥6 months. The meta-analysis included 23 studies (7,090 patients). Compared with BMS, DES-treated patients had lower rates of TVR (odds ratio (OR), 0.53; confidence interval (CI), 0.39-0.72; P

AB - Background: Evidence supporting the use of drug-eluting stents (DES) in saphenous vein graft (SVG) disease is uncertain. Previous studies have suggested that DES might reduce the re-intervention rate in SVG disease, with conflicting data on mortality. Thus, a meta-analysis was performed to compare outcomes of DES vs. bare metal stent (BMS) in SVG disease. Methods and Results: Medline and Web databases were searched for studies comparing DES and BMS for SVG disease, reporting rates of overall mortality, target vessel revascularization (TVR) and myocardial infarction (MI) with a follow-up of ≥6 months. The meta-analysis included 23 studies (7,090 patients). Compared with BMS, DES-treated patients had lower rates of TVR (odds ratio (OR), 0.53; confidence interval (CI), 0.39-0.72; P

KW - Angioplasty

KW - Coronary artery bypass grafting

KW - Drug-eluting stents

KW - Meta-analysis

KW - Stents

UR - http://www.scopus.com/inward/record.url?scp=79251569595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79251569595&partnerID=8YFLogxK

U2 - 10.1253/circj.CJ-10-0186

DO - 10.1253/circj.CJ-10-0186

M3 - Article

C2 - 21173499

AN - SCOPUS:79251569595

VL - 75

SP - 280

EP - 289

JO - Circulation Journal

JF - Circulation Journal

SN - 1346-9843

IS - 2

ER -