Abstract
Background: Evidence supporting the use of drug-eluting stents (DES) in saphenous vein graft (SVG) disease is uncertain. Previous studies have suggested that DES might reduce the re-intervention rate in SVG disease, with conflicting data on mortality. Thus, a meta-analysis was performed to compare outcomes of DES vs. bare metal stent (BMS) in SVG disease. Methods and Results: Medline and Web databases were searched for studies comparing DES and BMS for SVG disease, reporting rates of overall mortality, target vessel revascularization (TVR) and myocardial infarction (MI) with a follow-up of ≥6 months. The meta-analysis included 23 studies (7,090 patients). Compared with BMS, DES-treated patients had lower rates of TVR (odds ratio (OR), 0.53; confidence interval (CI), 0.39-0.72; P
Original language | English |
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Pages (from-to) | 280-289 |
Number of pages | 10 |
Journal | Circulation Journal |
Volume | 75 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 2011 |
Keywords
- Angioplasty
- Coronary artery bypass grafting
- Drug-eluting stents
- Meta-analysis
- Stents
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine