Drug use and upper gastrointestinal complications in children: A case-control study

Francesca Menniti-Ippolito; Roberto Da Cas; Luciano Sagliocca; Giuseppe Traversa; Fernanda Ferrazin; Carmela Santuccio; Loriana Tartaglia; Francesco Trotta; Pasquale Di Pietro; Salvatore Renna; Rossella Rossi; Bianca Domenichini; Stefania Gamba; Francesco Trovato; Pier Angelo Tovo; Manuela Bianciotto; Carmelina Calitri; Clara Gabiano; Irene Raffaldi; Antonio Urbino; Liviana Da Dalt; Valentina Favero; Laura Giordano; Maura Baraldi; Federica Bertuola; Eleonora Lorenzon; Francesca Parata; Giorgio Perilongo; Silvia Vendramin; Monica Frassineti; Anna Maria Calvani; Elena Chiappini; Maurizio De Martino; Claudia Fancelli; Francesco Mannelli; Rachele Mazzantini; Sara Sollai; Elisabetta Venturini; Nicola Pirozzi; Umberto Raucci; Antonino Reale; Rossella Rossi; Nadia Mores; Giulia Bersani; Alessia De Nisco; Antonio Chiaretti; Riccardo Riccardi; Costantino Romagnoli; Vincenzo Tipo; Michele Dinardo; Teresa Pisapia; Annalisa Capuano; Elisabetta Parretta; Concita Rafaniello; Fortunata Fucà; Eleonora Di Rosa

doi:10.1136/archdischild-2012-302100

Drug use and upper gastrointestinal complications in children: A case-control study

Francesca Menniti-Ippolito, Roberto Da Cas, Luciano Sagliocca, Giuseppe Traversa, Fernanda Ferrazin, Carmela Santuccio, Loriana Tartaglia, Francesco Trotta, Pasquale Di Pietro, Salvatore Renna, Rossella Rossi, Bianca Domenichini, Stefania Gamba, Francesco Trovato, Pier Angelo Tovo, Manuela Bianciotto, Carmelina Calitri, Clara Gabiano, Irene Raffaldi, Antonio UrbinoLiviana Da Dalt, Valentina Favero, Laura Giordano, Maura Baraldi, Federica Bertuola, Eleonora Lorenzon, Francesca Parata, Giorgio Perilongo, Silvia Vendramin, Monica Frassineti, Anna Maria Calvani, Elena Chiappini, Maurizio De Martino, Claudia Fancelli, Francesco Mannelli, Rachele Mazzantini, Sara Sollai, Elisabetta Venturini, Nicola Pirozzi, Umberto Raucci, Antonino Reale, Rossella Rossi, Nadia Mores, Giulia Bersani, Alessia De Nisco, Antonio Chiaretti, Riccardo Riccardi, Costantino Romagnoli, Vincenzo Tipo, Michele Dinardo, Teresa Pisapia, Annalisa Capuano, Elisabetta Parretta, Concita Rafaniello, Fortunata Fucà, Eleonora Di Rosa

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To evaluate the risk of upper gastrointestinal complications (UGIC) associated with drug use in the paediatric population. Methods: This study is part of a large Italian prospective multicentre study. The study population included children hospitalised for acute conditions through the emergency departments of eight clinical centres. Patients admitted for UGIC (defined as endoscopically confirmed gastroduodenal lesions or clinically defined haematemesis or melena) comprised the case series; children hospitalised for neurological disorders formed the control group. Information on drug and vaccine exposure was collected through parental interview during the children's hospitalisation. Logistic regression was used to estimate ORs for the occurrence of UGIC associated with drug use adjusted for age, clinical centre and concomitant use of any drug. Results: 486 children hospitalised for UGIC and 1930 for neurological disorders were enrolled between November 1999 and November 2010. Drug use was higher in cases than in controls (73% vs 54%; p

Original language	English
Pages (from-to)	218-221
Number of pages	4
Journal	Archives of Disease in Childhood
Volume	98
Issue number	3
DOIs	https://doi.org/10.1136/archdischild-2012-302100
Publication status	Published - Mar 2013

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

Access to Document

10.1136/archdischild-2012-302100

Cite this

Menniti-Ippolito, F., Da Cas, R., Sagliocca, L., Traversa, G., Ferrazin, F., Santuccio, C., Tartaglia, L., Trotta, F., Di Pietro, P., Renna, S., Rossi, R., Domenichini, B., Gamba, S., Trovato, F., Tovo, P. A., Bianciotto, M., Calitri, C., Gabiano, C., Raffaldi, I., ... Di Rosa, E. (2013). Drug use and upper gastrointestinal complications in children: A case-control study. Archives of Disease in Childhood, 98(3), 218-221. https://doi.org/10.1136/archdischild-2012-302100

Drug use and upper gastrointestinal complications in children : A case-control study. / Menniti-Ippolito, Francesca; Da Cas, Roberto; Sagliocca, Luciano; Traversa, Giuseppe; Ferrazin, Fernanda; Santuccio, Carmela; Tartaglia, Loriana; Trotta, Francesco; Di Pietro, Pasquale; Renna, Salvatore; Rossi, Rossella; Domenichini, Bianca; Gamba, Stefania; Trovato, Francesco; Tovo, Pier Angelo; Bianciotto, Manuela; Calitri, Carmelina; Gabiano, Clara; Raffaldi, Irene; Urbino, Antonio; Da Dalt, Liviana; Favero, Valentina; Giordano, Laura; Baraldi, Maura; Bertuola, Federica; Lorenzon, Eleonora; Parata, Francesca; Perilongo, Giorgio; Vendramin, Silvia; Frassineti, Monica; Calvani, Anna Maria; Chiappini, Elena; De Martino, Maurizio; Fancelli, Claudia; Mannelli, Francesco; Mazzantini, Rachele; Sollai, Sara; Venturini, Elisabetta; Pirozzi, Nicola; Raucci, Umberto; Reale, Antonino; Rossi, Rossella; Mores, Nadia; Bersani, Giulia; De Nisco, Alessia; Chiaretti, Antonio; Riccardi, Riccardo; Romagnoli, Costantino; Tipo, Vincenzo; Dinardo, Michele; Pisapia, Teresa; Capuano, Annalisa; Parretta, Elisabetta; Rafaniello, Concita; Fucà, Fortunata; Di Rosa, Eleonora.

In: Archives of Disease in Childhood, Vol. 98, No. 3, 03.2013, p. 218-221.

Research output: Contribution to journal › Article › peer-review

Menniti-Ippolito, F, Da Cas, R, Sagliocca, L, Traversa, G, Ferrazin, F, Santuccio, C, Tartaglia, L, Trotta, F, Di Pietro, P, Renna, S, Rossi, R, Domenichini, B, Gamba, S, Trovato, F, Tovo, PA, Bianciotto, M, Calitri, C, Gabiano, C, Raffaldi, I, Urbino, A, Da Dalt, L, Favero, V, Giordano, L, Baraldi, M, Bertuola, F, Lorenzon, E, Parata, F, Perilongo, G, Vendramin, S, Frassineti, M, Calvani, AM, Chiappini, E, De Martino, M, Fancelli, C, Mannelli, F, Mazzantini, R, Sollai, S, Venturini, E, Pirozzi, N, Raucci, U, Reale, A, Rossi, R, Mores, N, Bersani, G, De Nisco, A, Chiaretti, A, Riccardi, R, Romagnoli, C, Tipo, V, Dinardo, M, Pisapia, T, Capuano, A, Parretta, E, Rafaniello, C, Fucà, F & Di Rosa, E 2013, 'Drug use and upper gastrointestinal complications in children: A case-control study', Archives of Disease in Childhood, vol. 98, no. 3, pp. 218-221. https://doi.org/10.1136/archdischild-2012-302100

Menniti-Ippolito, Francesca ; Da Cas, Roberto ; Sagliocca, Luciano ; Traversa, Giuseppe ; Ferrazin, Fernanda ; Santuccio, Carmela ; Tartaglia, Loriana ; Trotta, Francesco ; Di Pietro, Pasquale ; Renna, Salvatore ; Rossi, Rossella ; Domenichini, Bianca ; Gamba, Stefania ; Trovato, Francesco ; Tovo, Pier Angelo ; Bianciotto, Manuela ; Calitri, Carmelina ; Gabiano, Clara ; Raffaldi, Irene ; Urbino, Antonio ; Da Dalt, Liviana ; Favero, Valentina ; Giordano, Laura ; Baraldi, Maura ; Bertuola, Federica ; Lorenzon, Eleonora ; Parata, Francesca ; Perilongo, Giorgio ; Vendramin, Silvia ; Frassineti, Monica ; Calvani, Anna Maria ; Chiappini, Elena ; De Martino, Maurizio ; Fancelli, Claudia ; Mannelli, Francesco ; Mazzantini, Rachele ; Sollai, Sara ; Venturini, Elisabetta ; Pirozzi, Nicola ; Raucci, Umberto ; Reale, Antonino ; Rossi, Rossella ; Mores, Nadia ; Bersani, Giulia ; De Nisco, Alessia ; Chiaretti, Antonio ; Riccardi, Riccardo ; Romagnoli, Costantino ; Tipo, Vincenzo ; Dinardo, Michele ; Pisapia, Teresa ; Capuano, Annalisa ; Parretta, Elisabetta ; Rafaniello, Concita ; Fucà, Fortunata ; Di Rosa, Eleonora. / Drug use and upper gastrointestinal complications in children : A case-control study. In: Archives of Disease in Childhood. 2013 ; Vol. 98, No. 3. pp. 218-221.

@article{ab2d1f5d08b24909844ca51174c32352,

title = "Drug use and upper gastrointestinal complications in children: A case-control study",

abstract = "Objective: To evaluate the risk of upper gastrointestinal complications (UGIC) associated with drug use in the paediatric population. Methods: This study is part of a large Italian prospective multicentre study. The study population included children hospitalised for acute conditions through the emergency departments of eight clinical centres. Patients admitted for UGIC (defined as endoscopically confirmed gastroduodenal lesions or clinically defined haematemesis or melena) comprised the case series; children hospitalised for neurological disorders formed the control group. Information on drug and vaccine exposure was collected through parental interview during the children's hospitalisation. Logistic regression was used to estimate ORs for the occurrence of UGIC associated with drug use adjusted for age, clinical centre and concomitant use of any drug. Results: 486 children hospitalised for UGIC and 1930 for neurological disorders were enrolled between November 1999 and November 2010. Drug use was higher in cases than in controls (73% vs 54%; p",

author = "Francesca Menniti-Ippolito and {Da Cas}, Roberto and Luciano Sagliocca and Giuseppe Traversa and Fernanda Ferrazin and Carmela Santuccio and Loriana Tartaglia and Francesco Trotta and {Di Pietro}, Pasquale and Salvatore Renna and Rossella Rossi and Bianca Domenichini and Stefania Gamba and Francesco Trovato and Tovo, {Pier Angelo} and Manuela Bianciotto and Carmelina Calitri and Clara Gabiano and Irene Raffaldi and Antonio Urbino and {Da Dalt}, Liviana and Valentina Favero and Laura Giordano and Maura Baraldi and Federica Bertuola and Eleonora Lorenzon and Francesca Parata and Giorgio Perilongo and Silvia Vendramin and Monica Frassineti and Calvani, {Anna Maria} and Elena Chiappini and {De Martino}, Maurizio and Claudia Fancelli and Francesco Mannelli and Rachele Mazzantini and Sara Sollai and Elisabetta Venturini and Nicola Pirozzi and Umberto Raucci and Antonino Reale and Rossella Rossi and Nadia Mores and Giulia Bersani and {De Nisco}, Alessia and Antonio Chiaretti and Riccardo Riccardi and Costantino Romagnoli and Vincenzo Tipo and Michele Dinardo and Teresa Pisapia and Annalisa Capuano and Elisabetta Parretta and Concita Rafaniello and Fortunata Fuc{\`a} and {Di Rosa}, Eleonora",

year = "2013",

month = mar,

doi = "10.1136/archdischild-2012-302100",

language = "English",

volume = "98",

pages = "218--221",

journal = "Archives of Disease in Childhood",

issn = "0003-9888",

publisher = "BMJ Publishing Group",

number = "3",

}

TY - JOUR

T1 - Drug use and upper gastrointestinal complications in children

T2 - A case-control study

AU - Menniti-Ippolito, Francesca

AU - Da Cas, Roberto

AU - Sagliocca, Luciano

AU - Traversa, Giuseppe

AU - Ferrazin, Fernanda

AU - Santuccio, Carmela

AU - Tartaglia, Loriana

AU - Trotta, Francesco

AU - Di Pietro, Pasquale

AU - Renna, Salvatore

AU - Rossi, Rossella

AU - Domenichini, Bianca

AU - Gamba, Stefania

AU - Trovato, Francesco

AU - Tovo, Pier Angelo

AU - Bianciotto, Manuela

AU - Calitri, Carmelina

AU - Gabiano, Clara

AU - Raffaldi, Irene

AU - Urbino, Antonio

AU - Da Dalt, Liviana

AU - Favero, Valentina

AU - Giordano, Laura

AU - Baraldi, Maura

AU - Bertuola, Federica

AU - Lorenzon, Eleonora

AU - Parata, Francesca

AU - Perilongo, Giorgio

AU - Vendramin, Silvia

AU - Frassineti, Monica

AU - Calvani, Anna Maria

AU - Chiappini, Elena

AU - De Martino, Maurizio

AU - Fancelli, Claudia

AU - Mannelli, Francesco

AU - Mazzantini, Rachele

AU - Sollai, Sara

AU - Venturini, Elisabetta

AU - Pirozzi, Nicola

AU - Raucci, Umberto

AU - Reale, Antonino

AU - Rossi, Rossella

AU - Mores, Nadia

AU - Bersani, Giulia

AU - De Nisco, Alessia

AU - Chiaretti, Antonio

AU - Riccardi, Riccardo

AU - Romagnoli, Costantino

AU - Tipo, Vincenzo

AU - Dinardo, Michele

AU - Pisapia, Teresa

AU - Capuano, Annalisa

AU - Parretta, Elisabetta

AU - Rafaniello, Concita

AU - Fucà, Fortunata

AU - Di Rosa, Eleonora

PY - 2013/3

Y1 - 2013/3

N2 - Objective: To evaluate the risk of upper gastrointestinal complications (UGIC) associated with drug use in the paediatric population. Methods: This study is part of a large Italian prospective multicentre study. The study population included children hospitalised for acute conditions through the emergency departments of eight clinical centres. Patients admitted for UGIC (defined as endoscopically confirmed gastroduodenal lesions or clinically defined haematemesis or melena) comprised the case series; children hospitalised for neurological disorders formed the control group. Information on drug and vaccine exposure was collected through parental interview during the children's hospitalisation. Logistic regression was used to estimate ORs for the occurrence of UGIC associated with drug use adjusted for age, clinical centre and concomitant use of any drug. Results: 486 children hospitalised for UGIC and 1930 for neurological disorders were enrolled between November 1999 and November 2010. Drug use was higher in cases than in controls (73% vs 54%; p

AB - Objective: To evaluate the risk of upper gastrointestinal complications (UGIC) associated with drug use in the paediatric population. Methods: This study is part of a large Italian prospective multicentre study. The study population included children hospitalised for acute conditions through the emergency departments of eight clinical centres. Patients admitted for UGIC (defined as endoscopically confirmed gastroduodenal lesions or clinically defined haematemesis or melena) comprised the case series; children hospitalised for neurological disorders formed the control group. Information on drug and vaccine exposure was collected through parental interview during the children's hospitalisation. Logistic regression was used to estimate ORs for the occurrence of UGIC associated with drug use adjusted for age, clinical centre and concomitant use of any drug. Results: 486 children hospitalised for UGIC and 1930 for neurological disorders were enrolled between November 1999 and November 2010. Drug use was higher in cases than in controls (73% vs 54%; p

UR - http://www.scopus.com/inward/record.url?scp=84874655412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874655412&partnerID=8YFLogxK

U2 - 10.1136/archdischild-2012-302100

DO - 10.1136/archdischild-2012-302100

M3 - Article

C2 - 23264432

AN - SCOPUS:84874655412

VL - 98

SP - 218

EP - 221

JO - Archives of Disease in Childhood

JF - Archives of Disease in Childhood

SN - 0003-9888

IS - 3

ER -

Drug use and upper gastrointestinal complications in children: A case-control study

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this