Dry eye in vernal keratoconjunctivitis

Edoardo Villani, Marika Dello Strologo, Francesco Pichi, Saverio V. Luccarelli, Stefano De Cilla, Massimiliano Serafino, Paolo Nucci

Research output: Contribution to journalArticlepeer-review


The purpose of this comparative cross-sectional study was to investigate the use of standardized clinical tests for dry eye in pediatric patients with active and quiet vernal keratoconjunctivitis (VKC) and to compare them with healthy children. We recruited 35 active VKC, 35 inactive VKC, and 70 age-matched control healthy subjects. Each child underwent a complete eye examination, including visual analog scale symptoms assessment, biomicroscopy, fluorescein break-up time (BUT), corneal fluorescein and conjunctival lissamine green staining, corneal esthesiometry, Schirmer test with anesthetic, and meibomian glands inspection and expression. Active VKC patients showed significantly increased symptoms and signs of ocular surface disease, compared with the other 2 groups. Inactive VKC patients, compared with control subjects, showed increased photophobia (P

Original languageEnglish
Pages (from-to)e1648
JournalMedicine (United States)
Issue number42
Publication statusPublished - Oct 1 2015

ASJC Scopus subject areas

  • Medicine(all)


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