Dual antiplatelet regime versus acetyl-acetic acid for carotid artery stenting

Ilias Dalainas, Giovanni Nano, Paolo Bianchi, Silvia Stegher, Giovanni Malacrida, Domenico G. Tealdi

Research output: Contribution to journalArticlepeer-review

Abstract

Carotid artery stenting has been proposed as an option treatment of carotid artery stenosis. The aim of this single-institution study is to compare the dual-antiplatelet treatment and heparin combined with acetyl-acetic acid, in patients who underwent carotid artery stenting. We compared 2 groups of 50 patents each who underwent carotid artery stenting for primary atherosclerotic disease. Group A received heparin for 24 h combined with 325 mg acetyl-acetic acid and group B received 250 mg ticlopidine twice a day combined with 325 mg acetyl-acetic acid. Outcome measurements included 30-day bleeding and neurological complications and 30-day thrombosis/occlusion rates. The neurological complications were 16% in group A and 2% in group B (p <0.05). Bleeding complications occurred in 4% in group A and 2% in group B (p > 0.05). The 30-day thrombosis/occlusion rate was 2% in group A and 0% in group B (p > 0.05). Dual antiplatelet treatment is recommended in all patients undergoing carotid artery stenting.

Original languageEnglish
Pages (from-to)519-521
Number of pages3
JournalCardioVascular and Interventional Radiology
Volume29
Issue number4
DOIs
Publication statusPublished - Aug 2006

Keywords

  • Antiplatelet agents
  • Carotid disease
  • Carotid stenting

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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