Ductal carcinoma in situ: MR imaging - Histopathologic correlation

R. Gilles, B. Zafrani, J. M. Guinebretiere, M. Meunier, O. Lucidarme, A. A. Tardivon, F. Rochard, D. Vanel, S. Neuenschwander, R. Arriagada

Research output: Contribution to journalArticle

229 Citations (Scopus)

Abstract

PURPOSE: To correlate histopathologic and magnetic resonance (MR) imaging findings of ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: Thirty- six women with DCIS underwent preoperative contrast material-enhanced subtraction dynamic MR imaging. Concomitant early contrast enhancement in the breast parenchyma with normal vessels was considered a positive finding. The size and shape of early enhancement were correlated with the size and density packing of ducts involved by DCIS. Tumor angiogenesis in the stroma that surrounded the ducts was evaluated with immunoperoxidase staining. RESULTS: Early contrast enhancement was demonstrated in 34 patients with DCIS but not in two patients with comedo-type DCIS. Tumor angiogenesis was demonstrated in the stroma. The size and morphology of contrast-enhanced lesions significantly correlated with the size (P = .0085) and density packing of ducts involved by DCIS (P = .012). CONCLUSION: Contrast enhancement on dynamic MR images of DCIS may be due to the presence of tumor angiogenesis in the stroma.

Original languageEnglish
Pages (from-to)415-419
Number of pages5
JournalRadiology
Volume196
Issue number2
Publication statusPublished - 1995

Fingerprint

Carcinoma, Intraductal, Noninfiltrating
Magnetic Resonance Imaging
Neoplasms
Contrast Media
Breast
Magnetic Resonance Spectroscopy
Staining and Labeling

Keywords

  • Breast neoplasms
  • Breast neoplasms, diagnosis
  • Breast neoplasms, MR

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Gilles, R., Zafrani, B., Guinebretiere, J. M., Meunier, M., Lucidarme, O., Tardivon, A. A., ... Arriagada, R. (1995). Ductal carcinoma in situ: MR imaging - Histopathologic correlation. Radiology, 196(2), 415-419.

Ductal carcinoma in situ : MR imaging - Histopathologic correlation. / Gilles, R.; Zafrani, B.; Guinebretiere, J. M.; Meunier, M.; Lucidarme, O.; Tardivon, A. A.; Rochard, F.; Vanel, D.; Neuenschwander, S.; Arriagada, R.

In: Radiology, Vol. 196, No. 2, 1995, p. 415-419.

Research output: Contribution to journalArticle

Gilles, R, Zafrani, B, Guinebretiere, JM, Meunier, M, Lucidarme, O, Tardivon, AA, Rochard, F, Vanel, D, Neuenschwander, S & Arriagada, R 1995, 'Ductal carcinoma in situ: MR imaging - Histopathologic correlation', Radiology, vol. 196, no. 2, pp. 415-419.
Gilles R, Zafrani B, Guinebretiere JM, Meunier M, Lucidarme O, Tardivon AA et al. Ductal carcinoma in situ: MR imaging - Histopathologic correlation. Radiology. 1995;196(2):415-419.
Gilles, R. ; Zafrani, B. ; Guinebretiere, J. M. ; Meunier, M. ; Lucidarme, O. ; Tardivon, A. A. ; Rochard, F. ; Vanel, D. ; Neuenschwander, S. ; Arriagada, R. / Ductal carcinoma in situ : MR imaging - Histopathologic correlation. In: Radiology. 1995 ; Vol. 196, No. 2. pp. 415-419.
@article{63ac006433b843afac4c575cdce82fca,
title = "Ductal carcinoma in situ: MR imaging - Histopathologic correlation",
abstract = "PURPOSE: To correlate histopathologic and magnetic resonance (MR) imaging findings of ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: Thirty- six women with DCIS underwent preoperative contrast material-enhanced subtraction dynamic MR imaging. Concomitant early contrast enhancement in the breast parenchyma with normal vessels was considered a positive finding. The size and shape of early enhancement were correlated with the size and density packing of ducts involved by DCIS. Tumor angiogenesis in the stroma that surrounded the ducts was evaluated with immunoperoxidase staining. RESULTS: Early contrast enhancement was demonstrated in 34 patients with DCIS but not in two patients with comedo-type DCIS. Tumor angiogenesis was demonstrated in the stroma. The size and morphology of contrast-enhanced lesions significantly correlated with the size (P = .0085) and density packing of ducts involved by DCIS (P = .012). CONCLUSION: Contrast enhancement on dynamic MR images of DCIS may be due to the presence of tumor angiogenesis in the stroma.",
keywords = "Breast neoplasms, Breast neoplasms, diagnosis, Breast neoplasms, MR",
author = "R. Gilles and B. Zafrani and Guinebretiere, {J. M.} and M. Meunier and O. Lucidarme and Tardivon, {A. A.} and F. Rochard and D. Vanel and S. Neuenschwander and R. Arriagada",
year = "1995",
language = "English",
volume = "196",
pages = "415--419",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "2",

}

TY - JOUR

T1 - Ductal carcinoma in situ

T2 - MR imaging - Histopathologic correlation

AU - Gilles, R.

AU - Zafrani, B.

AU - Guinebretiere, J. M.

AU - Meunier, M.

AU - Lucidarme, O.

AU - Tardivon, A. A.

AU - Rochard, F.

AU - Vanel, D.

AU - Neuenschwander, S.

AU - Arriagada, R.

PY - 1995

Y1 - 1995

N2 - PURPOSE: To correlate histopathologic and magnetic resonance (MR) imaging findings of ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: Thirty- six women with DCIS underwent preoperative contrast material-enhanced subtraction dynamic MR imaging. Concomitant early contrast enhancement in the breast parenchyma with normal vessels was considered a positive finding. The size and shape of early enhancement were correlated with the size and density packing of ducts involved by DCIS. Tumor angiogenesis in the stroma that surrounded the ducts was evaluated with immunoperoxidase staining. RESULTS: Early contrast enhancement was demonstrated in 34 patients with DCIS but not in two patients with comedo-type DCIS. Tumor angiogenesis was demonstrated in the stroma. The size and morphology of contrast-enhanced lesions significantly correlated with the size (P = .0085) and density packing of ducts involved by DCIS (P = .012). CONCLUSION: Contrast enhancement on dynamic MR images of DCIS may be due to the presence of tumor angiogenesis in the stroma.

AB - PURPOSE: To correlate histopathologic and magnetic resonance (MR) imaging findings of ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: Thirty- six women with DCIS underwent preoperative contrast material-enhanced subtraction dynamic MR imaging. Concomitant early contrast enhancement in the breast parenchyma with normal vessels was considered a positive finding. The size and shape of early enhancement were correlated with the size and density packing of ducts involved by DCIS. Tumor angiogenesis in the stroma that surrounded the ducts was evaluated with immunoperoxidase staining. RESULTS: Early contrast enhancement was demonstrated in 34 patients with DCIS but not in two patients with comedo-type DCIS. Tumor angiogenesis was demonstrated in the stroma. The size and morphology of contrast-enhanced lesions significantly correlated with the size (P = .0085) and density packing of ducts involved by DCIS (P = .012). CONCLUSION: Contrast enhancement on dynamic MR images of DCIS may be due to the presence of tumor angiogenesis in the stroma.

KW - Breast neoplasms

KW - Breast neoplasms, diagnosis

KW - Breast neoplasms, MR

UR - http://www.scopus.com/inward/record.url?scp=0029087493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029087493&partnerID=8YFLogxK

M3 - Article

C2 - 7617854

AN - SCOPUS:0029087493

VL - 196

SP - 415

EP - 419

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 2

ER -