Duplication cyst of the stomach with respiratory epithelium in adult: An uncommon finding. Report of case and review of literature

Severino Montemurro, Carmine Cartanese, Raffaele De Luca, Francesco Alfredo Zito, Girolamo Ranieri, Eustachio Ruggieri

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Gastrointestinal duplication is a congenital rare disease entity. Duplication cyst of the stomach with pseudo stratified columnar ciliated epithelium is extremely rare. The very appearance of a gastric duplication cyst in an adult can present a diagnostic dilemma. In majority of reported cases, the diagnosis is established during surgical exploration. We report on a 34 year-old female patient suffering from repeated episodes of epigastric pain and gastroesophageal reflux. Abdominal computed tomography and endoscopic ultrasound demonstrated a intramural lesion attached to the gastric fundus, suggestive of gastrointestinal stromal tumor (GIST). At exploratory laparotomy a non-communicating cyst, was found along the greater curvature of the stomach in the esophagogastric transition. The lesion was excised along with an adjacent sleeve of the stomach and esophagus wall because shared muscular layer with the stomach and esophagus. The final pathologic examination revealed that the inner wall of the cyst was lined by a pseudostratified columnar ciliated epithelium (respiratory type) and, in part, columnar and gastric foveolar epithelium. Even though a panel of imaging modalities is available, it is still difficult to obtain a preoperative diagnosis. Duplication cyst can be mistaken for a soft tissue tumor of the gastrointestinal tract. There is no therapeutic algorithm. Surgical treatment is recommended for symptomatic cases.

Original languageEnglish
Pages (from-to)487-492
Number of pages6
JournalAnnali Italiani di Chirurgia
Issue number6
Publication statusPublished - Nov 2011


  • Duplication cyst
  • Gastric duplication
  • Respiratory epithelium

ASJC Scopus subject areas

  • Surgery

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