Duration of antiinflammatory and symptomatic effects after suspension of intranasal corticosteroid in persistent allergic rhinitis

Giorgio Ciprandi, Vittorio Ricca, Ferrero Paola, Bairo Alessandra, Anna Maria Riccio, Manlio Milanese, F. Frati, Maria Angela Tosca

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Allergic rhinitis is characterized by an inflammatory response consequent to allergen exposure. Intranasal corticosteroids represent a first line treatment, but there is no adequate knowledge concerning the duration of symptomatic and antiinflammatory effects after their suspension. Thus, we aimed at investigating this issue. Methods: Twelve children with persistent allergic rhinitis were treated with FPANS for 30 days and were followed for 12 days after its suspension. Nasal symptoms, considered as TSS, and inflammatory cells, recovered by nasal scraping, were evaluated. Results: FPANS significantly reduced TSS (p

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalEuropean Annals of Allergy and Clinical Immunology
Volume36
Issue number2
Publication statusPublished - Feb 2004

Keywords

  • Allergic rhinitis
  • Inflammatory cells
  • Nasal symptoms
  • Suspension
  • Topical corticosteroids

ASJC Scopus subject areas

  • Immunology and Allergy

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