Duration of immune protection after hepatitis B vaccine in newborns from HBsAg-positive carrier mothers.

C. Belloni; P. Orsolini; L. Soldini; D. Campisi; A. Chiesa; R. Ciceri; G. Filice

Duration of immune protection after hepatitis B vaccine in newborns from HBsAg-positive carrier mothers.

C. Belloni, P. Orsolini, L. Soldini, D. Campisi, A. Chiesa, R. Ciceri, G. Filice

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

A group of 43 healthy neonates born from HBsAg-positive mothers were evaluated for the presence of protective HBsAb titre after administration of hepatitis B plasma-derived vaccine and hepatitis B hyperimmune-globulin. At 36 months of life we found that a significant number of children had a low HBsAb serum level. This suggests that a close serologic follow-up is necessary to evaluate the optimal timing for the administration of a booster dose of the vaccine.

Original language	English
Pages (from-to)	195-198
Number of pages	4
Journal	Microbiologica
Volume	14
Issue number	3
Publication status	Published - Jul 1991

ASJC Scopus subject areas

Applied Microbiology and Biotechnology

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title = "Duration of immune protection after hepatitis B vaccine in newborns from HBsAg-positive carrier mothers.",

abstract = "A group of 43 healthy neonates born from HBsAg-positive mothers were evaluated for the presence of protective HBsAb titre after administration of hepatitis B plasma-derived vaccine and hepatitis B hyperimmune-globulin. At 36 months of life we found that a significant number of children had a low HBsAb serum level. This suggests that a close serologic follow-up is necessary to evaluate the optimal timing for the administration of a booster dose of the vaccine.",

author = "C. Belloni and P. Orsolini and L. Soldini and D. Campisi and A. Chiesa and R. Ciceri and G. Filice",

year = "1991",

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AU - Belloni, C.

AU - Orsolini, P.

AU - Soldini, L.

AU - Campisi, D.

AU - Chiesa, A.

AU - Ciceri, R.

AU - Filice, G.

PY - 1991/7

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N2 - A group of 43 healthy neonates born from HBsAg-positive mothers were evaluated for the presence of protective HBsAb titre after administration of hepatitis B plasma-derived vaccine and hepatitis B hyperimmune-globulin. At 36 months of life we found that a significant number of children had a low HBsAb serum level. This suggests that a close serologic follow-up is necessary to evaluate the optimal timing for the administration of a booster dose of the vaccine.

AB - A group of 43 healthy neonates born from HBsAg-positive mothers were evaluated for the presence of protective HBsAb titre after administration of hepatitis B plasma-derived vaccine and hepatitis B hyperimmune-globulin. At 36 months of life we found that a significant number of children had a low HBsAb serum level. This suggests that a close serologic follow-up is necessary to evaluate the optimal timing for the administration of a booster dose of the vaccine.

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