Dynamic changes in prefrontal cortex involvement during verbal episodic memory formation

Giulia Galli, Matteo Feurra, Enea Francesco Pavone, Miroslav Sirota, Simone Rossi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

During encoding, the neural activity immediately before or during an event can predict whether that event will be later remembered. The contribution of brain activity immediately after an event to memory formation is however less known. Here, we used repetitive Transcranial Magnetic Stimulation (rTMS) to investigate the temporal dynamics of episodic memory encoding with a focus on post-stimulus time intervals. At encoding, rTMS was applied during the online processing of the word, at its offset, or 100, 200, 300 or 400 ms thereafter. rTMS was delivered to the left ventrolateral (VLPFC) or dorsolateral prefrontal cortex (DLPFC). VLPFC rTMS during the first few hundreds of milliseconds after word offset disrupted subsequent recognition accuracy. We did not observe effects of DLPFC rTMS at any time point. These results suggest that encoding-related VLPFC engagement starts at a relatively late processing stage, and may reflect brain processes related to the offset of the stimulus.

Original languageEnglish
Pages (from-to)36-44
Number of pages9
JournalBiological Psychology
Volume125
DOIs
Publication statusPublished - Apr 1 2017

Fingerprint

Episodic Memory
Transcranial Magnetic Stimulation
Prefrontal Cortex
Word Processing
Brain

Keywords

  • Episodic memory
  • Memory formation
  • Prefrontal cortex
  • rTMS

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

Dynamic changes in prefrontal cortex involvement during verbal episodic memory formation. / Galli, Giulia; Feurra, Matteo; Pavone, Enea Francesco; Sirota, Miroslav; Rossi, Simone.

In: Biological Psychology, Vol. 125, 01.04.2017, p. 36-44.

Research output: Contribution to journalArticle

Galli, Giulia ; Feurra, Matteo ; Pavone, Enea Francesco ; Sirota, Miroslav ; Rossi, Simone. / Dynamic changes in prefrontal cortex involvement during verbal episodic memory formation. In: Biological Psychology. 2017 ; Vol. 125. pp. 36-44.
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