Dynamic contrast-enhanced mr imaging for soft tissue sarcomas

L. G. Shapeero, D. Vanel, K. L. Verstraete, J. L. Bloem

Research output: Contribution to journalArticlepeer-review


Dynamic contrast-enhanced magnetic resonance imaging has recently emerged as an important method for evaluating soft tissue sarcomas for biopsy localization, chemotherapeutic response, and long-term follow-up because of its ability to detect viable tumor. This article presents the basic principles of contrast kinetics in soft tissue sarcomas after bolus injection of contrast agent and discusses the current postprocessing methods (subtraction, first-pass image and time-intensity curves with region of interest, and color-encoded techniques) used to display these dynamic studies. Because of its excellent temporal resolution, dynamic MR imaging can delineate the early uptake of contrast agent in sarcomas within seconds after injection, almost synchronous with arterial enhancement, and thereby differentiate the rapidly enhancing viable tumor from the nonenhancing necrotic tumor and the late enhancing changes after surgery, radiation therapy, and chemotherapy.

Original languageEnglish
Pages (from-to)101-113
Number of pages13
JournalSeminars in Musculoskeletal Radiology
Issue number2
Publication statusPublished - 1999


  • Magnetic resonance (MR), rapid imaging
  • Sarcoma, soft tissue
  • Soft tissue sarcoma, chemotherapy
  • Soft tissue sarcoma, metastases
  • Soft tissue sarcoma, recurrences
  • Soft tissues, MR
  • Soft tissues, neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Surgery


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