Dynamic contrast-enhanced subtraction versus T2-weighted spin-echo MR imaging in the follow-up of colorectal neoplasm: A prospective study of 41 patients

Karen Kinkel, Anne A. Tardivon, Philippe Soyer, Alain Spatz, Philippe Lasser, Philippe Rougier, Daniel Vanel

Research output: Contribution to journalArticle

Abstract

PURPOSE: To compare dynamic contrast-enhanced subtraction (DCES) and T2- weighted spin-echo (SE) magnetic resonance (MR) imaging in the differentiation of fibrosis from recurrence during the follow-up of treated colorectal neoplasms. MATERIALS AND METHODS: Forty-one patients with 39 malignant and 16 benign lesions confirmed by means of surgery (n = 23), biopsy (n = 24), or 12-month follow-up examination (n = 8) underwent DCES MR imaging and T2-weighted SE MR imaging. Enhancement of an abnormal pelvic structure within the first 90 seconds on DCES images or high signal intensity on T2-weighted SE images was considered indicative of malignancy. RESULTS: Sensitivity, specificity, and positive and negative predictive values were, respectively, 97%, 81%, 93%, and 100% for DCES MR imaging and 77%, 56%, 81%, and 56% for T2-weighted MR imaging. The number of correctly classified lesions was significantly higher with DCES imaging compared with T2-weighted imaging (P ≤ .006). CONCLUSION: DCES imaging is more accurate than T2- weighted SE imaging for differentiating fibrosis from recurrence during the follow-up of treated colorectal neoplasms.

Original languageEnglish
Pages (from-to)453-458
Number of pages6
JournalRadiology
Volume200
Issue number2
Publication statusPublished - Aug 1996

Fingerprint

Colorectal Neoplasms
Magnetic Resonance Imaging
Prospective Studies
Fibrosis
Recurrence
Biopsy
Sensitivity and Specificity
Neoplasms

Keywords

  • Cadolinium
  • Colon, neoplasms
  • Magnetic resonance (MR), comparative studies
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), rapid imaging
  • Radiations, injurious effects, complications of therapeutic radiology
  • Rectum, neoplasms

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Kinkel, K., Tardivon, A. A., Soyer, P., Spatz, A., Lasser, P., Rougier, P., & Vanel, D. (1996). Dynamic contrast-enhanced subtraction versus T2-weighted spin-echo MR imaging in the follow-up of colorectal neoplasm: A prospective study of 41 patients. Radiology, 200(2), 453-458.

Dynamic contrast-enhanced subtraction versus T2-weighted spin-echo MR imaging in the follow-up of colorectal neoplasm : A prospective study of 41 patients. / Kinkel, Karen; Tardivon, Anne A.; Soyer, Philippe; Spatz, Alain; Lasser, Philippe; Rougier, Philippe; Vanel, Daniel.

In: Radiology, Vol. 200, No. 2, 08.1996, p. 453-458.

Research output: Contribution to journalArticle

Kinkel, K, Tardivon, AA, Soyer, P, Spatz, A, Lasser, P, Rougier, P & Vanel, D 1996, 'Dynamic contrast-enhanced subtraction versus T2-weighted spin-echo MR imaging in the follow-up of colorectal neoplasm: A prospective study of 41 patients', Radiology, vol. 200, no. 2, pp. 453-458.
Kinkel, Karen ; Tardivon, Anne A. ; Soyer, Philippe ; Spatz, Alain ; Lasser, Philippe ; Rougier, Philippe ; Vanel, Daniel. / Dynamic contrast-enhanced subtraction versus T2-weighted spin-echo MR imaging in the follow-up of colorectal neoplasm : A prospective study of 41 patients. In: Radiology. 1996 ; Vol. 200, No. 2. pp. 453-458.
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