Dynamic modulation of baroreflex sensitivity in health and disease

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Assessment of arterial baroreflex function in humans through laboratory tests has provided a great deal of information of pathophysiological and clinical relevance. Indeed, the sensitivity of the baroreceptor-heart rate reflex quantified through these laboratory methods was shown to predict the risk of cardiovascular events and death from myocardial infarction, heart failure, and in diabetic patients. This traditional approach, however, does not provide information on daily life baroreflex cardiovascular control. Modern techniques; based on computer analysis of spontaneous blood pressure and heart rate fluctuations, are now available and allow baroreflex sensitivity to be assessed under real-life conditions with no need for external stimulation. In particular, these methods offer the possibility of investigating the dynamic modulation of baroreflex sensitivity occurring either on a minute-to-minute basis or over 24 hours.

Original languageEnglish
Pages (from-to)469-487
Number of pages19
JournalAnnals of the New York Academy of Sciences
Volume940
Publication statusPublished - 2001

Fingerprint

Baroreflex
Modulation
Health
Heart Rate
Blood pressure
Pressoreceptors
Reflex
Heart Failure
Myocardial Infarction
Blood Pressure

Keywords

  • Acute myocardial infarction
  • Arterial baroreflex
  • Blood pressure variability
  • Essential hypertension
  • Heart rate variability
  • Sequence technique
  • Spectral analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Dynamic modulation of baroreflex sensitivity in health and disease. / Parati, Gianfranco; Di Rienzo, Marco; Mancia, Giuseppe.

In: Annals of the New York Academy of Sciences, Vol. 940, 2001, p. 469-487.

Research output: Contribution to journalArticle

@article{5bb573678fa44a5abffa4de64c17ec41,
title = "Dynamic modulation of baroreflex sensitivity in health and disease",
abstract = "Assessment of arterial baroreflex function in humans through laboratory tests has provided a great deal of information of pathophysiological and clinical relevance. Indeed, the sensitivity of the baroreceptor-heart rate reflex quantified through these laboratory methods was shown to predict the risk of cardiovascular events and death from myocardial infarction, heart failure, and in diabetic patients. This traditional approach, however, does not provide information on daily life baroreflex cardiovascular control. Modern techniques; based on computer analysis of spontaneous blood pressure and heart rate fluctuations, are now available and allow baroreflex sensitivity to be assessed under real-life conditions with no need for external stimulation. In particular, these methods offer the possibility of investigating the dynamic modulation of baroreflex sensitivity occurring either on a minute-to-minute basis or over 24 hours.",
keywords = "Acute myocardial infarction, Arterial baroreflex, Blood pressure variability, Essential hypertension, Heart rate variability, Sequence technique, Spectral analysis",
author = "Gianfranco Parati and {Di Rienzo}, Marco and Giuseppe Mancia",
year = "2001",
language = "English",
volume = "940",
pages = "469--487",
journal = "Annals of the New York Academy of Sciences",
issn = "0077-8923",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Dynamic modulation of baroreflex sensitivity in health and disease

AU - Parati, Gianfranco

AU - Di Rienzo, Marco

AU - Mancia, Giuseppe

PY - 2001

Y1 - 2001

N2 - Assessment of arterial baroreflex function in humans through laboratory tests has provided a great deal of information of pathophysiological and clinical relevance. Indeed, the sensitivity of the baroreceptor-heart rate reflex quantified through these laboratory methods was shown to predict the risk of cardiovascular events and death from myocardial infarction, heart failure, and in diabetic patients. This traditional approach, however, does not provide information on daily life baroreflex cardiovascular control. Modern techniques; based on computer analysis of spontaneous blood pressure and heart rate fluctuations, are now available and allow baroreflex sensitivity to be assessed under real-life conditions with no need for external stimulation. In particular, these methods offer the possibility of investigating the dynamic modulation of baroreflex sensitivity occurring either on a minute-to-minute basis or over 24 hours.

AB - Assessment of arterial baroreflex function in humans through laboratory tests has provided a great deal of information of pathophysiological and clinical relevance. Indeed, the sensitivity of the baroreceptor-heart rate reflex quantified through these laboratory methods was shown to predict the risk of cardiovascular events and death from myocardial infarction, heart failure, and in diabetic patients. This traditional approach, however, does not provide information on daily life baroreflex cardiovascular control. Modern techniques; based on computer analysis of spontaneous blood pressure and heart rate fluctuations, are now available and allow baroreflex sensitivity to be assessed under real-life conditions with no need for external stimulation. In particular, these methods offer the possibility of investigating the dynamic modulation of baroreflex sensitivity occurring either on a minute-to-minute basis or over 24 hours.

KW - Acute myocardial infarction

KW - Arterial baroreflex

KW - Blood pressure variability

KW - Essential hypertension

KW - Heart rate variability

KW - Sequence technique

KW - Spectral analysis

UR - http://www.scopus.com/inward/record.url?scp=0034941647&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034941647&partnerID=8YFLogxK

M3 - Article

VL - 940

SP - 469

EP - 487

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

SN - 0077-8923

ER -