Dynamic testing in the evaluation of male gonadal function.

M. U. De Martino, R. Pastore, M. Caprio, G. Frajese, A. Fabbri

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The maturation and physiologic functions of male sexual apparatus are under the control of the hypothalamic-pituitary-gonadal (HPG) axis. The determination of gonadotropins and testosterone as secretory products of pituitary and gonads, respectively, represents the first step in the evaluation of male sexual function and the diagnosis of disorders in male reproductive axis. However, there are several clinical situations that require a dynamic evaluation of this system and the measurement of basal gonadotropins and testosterone must be combined with specific dynamic tests. These mainly consist in GnRH stimulation, which evaluates the endocrine reserve capacity of the pituitary, and human chorionic gonadotropin (hCG) stimulation, which is used in the assessment of Leydig cells activity. The paper illustrates the technical aspects, the normal/pathological responses and the role of these two tests in assessing the male HPG axis in respect to different clinical diagnostic queries.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalJournal of Endocrinological Investigation
Volume26
Issue number7 Suppl
Publication statusPublished - 2003

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Gonadotropins
Testosterone
Leydig Cells
Gonads
Chorionic Gonadotropin
Gonadotropin-Releasing Hormone

ASJC Scopus subject areas

  • Endocrinology

Cite this

De Martino, M. U., Pastore, R., Caprio, M., Frajese, G., & Fabbri, A. (2003). Dynamic testing in the evaluation of male gonadal function. Journal of Endocrinological Investigation, 26(7 Suppl), 107-113.

Dynamic testing in the evaluation of male gonadal function. / De Martino, M. U.; Pastore, R.; Caprio, M.; Frajese, G.; Fabbri, A.

In: Journal of Endocrinological Investigation, Vol. 26, No. 7 Suppl, 2003, p. 107-113.

Research output: Contribution to journalArticle

De Martino, MU, Pastore, R, Caprio, M, Frajese, G & Fabbri, A 2003, 'Dynamic testing in the evaluation of male gonadal function.', Journal of Endocrinological Investigation, vol. 26, no. 7 Suppl, pp. 107-113.
De Martino MU, Pastore R, Caprio M, Frajese G, Fabbri A. Dynamic testing in the evaluation of male gonadal function. Journal of Endocrinological Investigation. 2003;26(7 Suppl):107-113.
De Martino, M. U. ; Pastore, R. ; Caprio, M. ; Frajese, G. ; Fabbri, A. / Dynamic testing in the evaluation of male gonadal function. In: Journal of Endocrinological Investigation. 2003 ; Vol. 26, No. 7 Suppl. pp. 107-113.
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