Abstract
Medically unexplained chronic disorders remain a challenge for clinicians because the patients with these syndromes have a wide range of symptoms, including pain, impaired concentration, sleep disturbances, fatigue and mood disorders, as well as functional problems and difficulties in carrying out the activities of daily living. Such disorders are the result of a complex physiological interaction of central and peripheral nervous signalling that leads to a highly individual symptom complex, although some of them seem to be related to one another, especially in terms of the mechanism of chronicity and pain amplification, and the co-occurrence of fatigue, sleep alterations, mood disturbances and cognitive impairment. This review will discuss the recent literature concerning the most common dysfunctional disorders: fibromyalgia syndrome, myalgic encephalomyelitis/ chronic fatigue syndrome, and irritable bowel syndrome.
| Original language | English |
|---|---|
| Journal | Clinical and Experimental Rheumatology |
| Volume | 30 |
| Issue number | SUPPL.74 |
| Publication status | Published - 2012 |
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Keywords
- Dysfunctional syndromes
- Fibromyalgia
ASJC Scopus subject areas
- Rheumatology
- Immunology
- Immunology and Allergy
Cite this
Dysfunctional syndromes and fibromyalgia : A 2012 critical digest. / Sarzi-Puttini, Piercarlo; Atzeni, Fabiola; Di Franco, Manuela; Buskila, Dan; Alciati, Alessandra; Giacomelli, Camillo; Rossi, Alessandra; Bazzichi, Laura.
In: Clinical and Experimental Rheumatology, Vol. 30, No. SUPPL.74, 2012.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Dysfunctional syndromes and fibromyalgia
T2 - A 2012 critical digest
AU - Sarzi-Puttini, Piercarlo
AU - Atzeni, Fabiola
AU - Di Franco, Manuela
AU - Buskila, Dan
AU - Alciati, Alessandra
AU - Giacomelli, Camillo
AU - Rossi, Alessandra
AU - Bazzichi, Laura
PY - 2012
Y1 - 2012
N2 - Medically unexplained chronic disorders remain a challenge for clinicians because the patients with these syndromes have a wide range of symptoms, including pain, impaired concentration, sleep disturbances, fatigue and mood disorders, as well as functional problems and difficulties in carrying out the activities of daily living. Such disorders are the result of a complex physiological interaction of central and peripheral nervous signalling that leads to a highly individual symptom complex, although some of them seem to be related to one another, especially in terms of the mechanism of chronicity and pain amplification, and the co-occurrence of fatigue, sleep alterations, mood disturbances and cognitive impairment. This review will discuss the recent literature concerning the most common dysfunctional disorders: fibromyalgia syndrome, myalgic encephalomyelitis/ chronic fatigue syndrome, and irritable bowel syndrome.
AB - Medically unexplained chronic disorders remain a challenge for clinicians because the patients with these syndromes have a wide range of symptoms, including pain, impaired concentration, sleep disturbances, fatigue and mood disorders, as well as functional problems and difficulties in carrying out the activities of daily living. Such disorders are the result of a complex physiological interaction of central and peripheral nervous signalling that leads to a highly individual symptom complex, although some of them seem to be related to one another, especially in terms of the mechanism of chronicity and pain amplification, and the co-occurrence of fatigue, sleep alterations, mood disturbances and cognitive impairment. This review will discuss the recent literature concerning the most common dysfunctional disorders: fibromyalgia syndrome, myalgic encephalomyelitis/ chronic fatigue syndrome, and irritable bowel syndrome.
KW - Dysfunctional syndromes
KW - Fibromyalgia
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UR - http://www.scopus.com/inward/citedby.url?scp=84874961979&partnerID=8YFLogxK
M3 - Article
C2 - 23261014
AN - SCOPUS:84874961979
VL - 30
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - SUPPL.74
ER -