Dysontogenetic neoplasms of the thyroid gland in infancy: two case reports

Virgilio Pinelli, Vittorio Pierro, Sergio Bottero, Pasquale Marsella, Michele Camarda

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Two rare cases of benign dysontogenetic neoplasms of the thyroid gland in pediatric age are presented, which were observed at the E.N.T. department of the Bambino Gesù Hospital of Rome, and successfully operated. The first case turned out to be a dysembryoma, classified as monodermic because of its origin from derivatives of only one germinal layer, the entoderm. The second case, a teratoma, presented a high seric concentration of AFP as the consequence of the synthetic activity of the share of embryonal epatic tissue present in the neoformation. Criteria to distinguish thyroid from cervical teratomata and to classify the different types of dysontogenetic neoplasms are discussed. The usual clinical and pathological manifestations of teratomas of the neck in infancy are mentioned. The necessity of a prompt surgical removal and of pre- and postoperative thyroid function studies is mentioned.

Original languageEnglish
Pages (from-to)101-110
Number of pages10
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number1
Publication statusPublished - 1985


  • monodermic dysembryoma
  • teratoma
  • thyroid

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine
  • Surgery


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