Dystrophic epidermolysis bullosa in versa: A case report

G. F. Altomare, M. Polenghi, P. D. Pigatto, V. Nazzaro, F. Piattoni

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The inverse form of recessive dystrophic epidermolysis bullosa is a rare genodermatosis characterized by a smouldering course of integumcntal blistering with improvement of lesions in adulthood, preferential localizations of lesions in flexural areas, severe oral and esophageal mucosal involvement and nail dystrophy. We describe a 41-year-old patient showing all the typical features of this form of epidermolysis bullosa. Ultrastructural findings in specimens obtained from perilcsional and healthy skin were similar to those usually observed in the Hallopcau-Sicmcns form of epidermolysis bullosa. The patient has been treated with phenytoin for a period of 9 months with considerable improvement of the skin manifestations.

Original languageEnglish
Pages (from-to)145-148
Number of pages4
Issue number2
Publication statusPublished - 1990


  • Epidermolysis bullosa
  • Hallopeau-Siemens type
  • Phcnytoin

ASJC Scopus subject areas

  • Dermatology


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