EAMI-Exercise training in anterior myocardial infarction: An ongoing multicenter randomized study; Preliminary results on left ventricular function and remodeling

P. Giannuzzi, P. L. Temporelli, L. Tavazzi, U. Corra, M. Gattone, A. Imparato, A. Giordano, C. Schweiger, L. Sala, C. Malinverni

Research output: Contribution to journalArticlepeer-review

Abstract

To determine the effects of a 6-month exercise training program on left ventricular (LV) function and remodeling, 49 consecutive patients (pts) with first Q anterior myocardial infarction (51±8 years), in I-II NYHA class, were studied 4 to 8 weeks after the acute episode and 6 months later by 2D- ECHO and upright bicycle ergometric test. At entry, pts were randomly allocated to physical training (T=25pts) or control (C=24pts). Global endocardial surface area (ESA), LV volumes and EF, extent of abnormal wall motion (%WMA), of regional dilatation (%REG DIL), and the shape distortion (DIST) index were analyzed. After 6 months, a significant increase in work capacity (4,589±1,417 to 5,379±1,485 KPM/min, p2: 68±12 to 77±18 in C, 71±12 to 74±18 in T; %REG DIL: 39±20 to 49±24 in C, 32±12 to 35±23 in T; DIST index: 0.16±0.07 to 0.21±0.09 in C, 0.2±0.07 to 0.22±0.1 in T). These variables did not change in pts with >40%EF. Thus, from these preliminary data, pts with

Original languageEnglish
JournalChest
Volume101
Issue number5 SUPPL.
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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