EANM Dosimetry Committee series on standard operational procedures for internal dosimetry for (131)I mIBG treatment of neuroendocrine tumours.

Jonathan Gear, Carlo Chiesa, Michael Lassmann, Pablo Mínguez Gabiña, Johannes Tran-Gia, Caroline Stokke, Glenn Flux

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of the EANM Dosimetry Committee Series on "Standard Operational Procedures for Dosimetry" (SOP) is to provide advice to scientists and clinicians on how to perform patient-specific absorbed dose assessments. This SOP describes image and data acquisition parameters and dosimetry calculations to determine the absorbed doses delivered to whole-body, tumour and normal organs following a therapeutic administration of (131)I mIBG for the treatment of neuroblastoma or adult neuroendocrine tumours. Recommendations are based on evidence in recent literature where available and on expert opinion within the community. This SOP is intended to promote standardisation of practice within the community and as such is based on the facilities and expertise that should be available to any centre able to perform specialised treatments with radiopharmaceuticals and patient-specific dosimetry. A clinical example is given to demonstrate the application of the absorbed dose calculations.
Original languageEnglish
Pages (from-to)15
Number of pages1
JournalEJNMMI Physics
Volume7
Issue number1
DOIs
Publication statusPublished - Mar 1 2020

Keywords

  • Neuroblastoma
  • Neuroendocrine
  • Dosimetry
  • Iodine-131
  • mIBG
  • Molecular radiotherapy

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