Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient

Silvano Menni, Grazia Pistritto, Raffaele Gianotti, Luciana Ghio, Alberto Edefonti

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Abstract

We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.

Original languageEnglish
Pages (from-to)477-479
Number of pages3
JournalPediatric Dermatology
Volume14
Issue number6
Publication statusPublished - Nov 1997

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Levamisole
Vasculitis
Ear
Necrosis
Pediatrics
Nephrosis
Nephrotic Syndrome
Adrenal Cortex Hormones
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Dermatology
  • Pediatrics, Perinatology, and Child Health

Cite this

Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient. / Menni, Silvano; Pistritto, Grazia; Gianotti, Raffaele; Ghio, Luciana; Edefonti, Alberto.

In: Pediatric Dermatology, Vol. 14, No. 6, 11.1997, p. 477-479.

Research output: Contribution to journalArticle

Menni, Silvano ; Pistritto, Grazia ; Gianotti, Raffaele ; Ghio, Luciana ; Edefonti, Alberto. / Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient. In: Pediatric Dermatology. 1997 ; Vol. 14, No. 6. pp. 477-479.
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