Early and delayed complications of polypectomy in a community setting

The SPoC prospective multicentre trial

Arnaldo Amato, Franco Radaelli, Marco Dinelli, Cristiano Crosta, Gianpaolo Cengia, Paolo Beretta, Massimo Devani, Davide Lochis, Giampiero Manes, Lucia Fini, Silvia Paggi, Giovanni Rubis Passoni, Alessandro Repici, Alessandro Redaelli, Cestari Renzo Cestari, Prada Alberto Prada, Giordano Bernasconi, Stefano Pallotta, Carlotta Gebbia, Antonio Cambareri & 10 others Laura Rovedatti, Maurizio Perego, Chiara Viganò, Marco Antonio Zappa, Stefano Bargiggia, Fabrizio Parente, Spinzi Giancarlo Spinzi, Claudio Leoci, Walter Piubello, Grillo Simone Grillo

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Colonoscopic polypectomy is effective in reducing the incidence of and mortality from colorectal cancer, but is not complication-free. Aims: To evaluate the incidence of early and delayed polypectomy complications and factors associated with their occurrence in a community setting. Methods: Web-database collection of patients' and polyp's features in consecutive colonic polypectomies during a 3-month period in 18 endoscopy centres. Results: Data on 5178 polypectomies in 2692 patients (54.3% males, mean age 59 years) were collected. The majority of the polyps were 10 mm: OR 4.35, 95% CI 5.53-7.48) and, inversely, right-sided location (OR 0.58, 95% CI 0.36-0.94) were correlated with bleeding events. The use of antithrombotics was associated with 5-fold increased risk of delayed bleeding. Conclusions: In the community setting, polypectomy was associated with a 1.4% risk of major complications. Polyp size and, inversely, right-sided location were associated with early bleeding; the use of antithrombotics increased the risk of delayed events.

Original languageEnglish
Pages (from-to)43-48
Number of pages6
JournalDigestive and Liver Disease
Volume48
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Polyps
Multicenter Studies
Hemorrhage
Incidence
Endoscopy
Colorectal Neoplasms
Databases
Mortality

Keywords

  • Colonoscopic polypectomy
  • Polypectomy complications

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Early and delayed complications of polypectomy in a community setting : The SPoC prospective multicentre trial. / Amato, Arnaldo; Radaelli, Franco; Dinelli, Marco; Crosta, Cristiano; Cengia, Gianpaolo; Beretta, Paolo; Devani, Massimo; Lochis, Davide; Manes, Giampiero; Fini, Lucia; Paggi, Silvia; Passoni, Giovanni Rubis; Repici, Alessandro; Redaelli, Alessandro; Renzo Cestari, Cestari; Alberto Prada, Prada; Bernasconi, Giordano; Pallotta, Stefano; Gebbia, Carlotta; Cambareri, Antonio; Rovedatti, Laura; Perego, Maurizio; Viganò, Chiara; Zappa, Marco Antonio; Bargiggia, Stefano; Parente, Fabrizio; Giancarlo Spinzi, Spinzi; Leoci, Claudio; Piubello, Walter; Simone Grillo, Grillo.

In: Digestive and Liver Disease, Vol. 48, No. 1, 01.01.2016, p. 43-48.

Research output: Contribution to journalArticle

Amato, A, Radaelli, F, Dinelli, M, Crosta, C, Cengia, G, Beretta, P, Devani, M, Lochis, D, Manes, G, Fini, L, Paggi, S, Passoni, GR, Repici, A, Redaelli, A, Renzo Cestari, C, Alberto Prada, P, Bernasconi, G, Pallotta, S, Gebbia, C, Cambareri, A, Rovedatti, L, Perego, M, Viganò, C, Zappa, MA, Bargiggia, S, Parente, F, Giancarlo Spinzi, S, Leoci, C, Piubello, W & Simone Grillo, G 2016, 'Early and delayed complications of polypectomy in a community setting: The SPoC prospective multicentre trial', Digestive and Liver Disease, vol. 48, no. 1, pp. 43-48. https://doi.org/10.1016/j.dld.2015.09.007
Amato, Arnaldo ; Radaelli, Franco ; Dinelli, Marco ; Crosta, Cristiano ; Cengia, Gianpaolo ; Beretta, Paolo ; Devani, Massimo ; Lochis, Davide ; Manes, Giampiero ; Fini, Lucia ; Paggi, Silvia ; Passoni, Giovanni Rubis ; Repici, Alessandro ; Redaelli, Alessandro ; Renzo Cestari, Cestari ; Alberto Prada, Prada ; Bernasconi, Giordano ; Pallotta, Stefano ; Gebbia, Carlotta ; Cambareri, Antonio ; Rovedatti, Laura ; Perego, Maurizio ; Viganò, Chiara ; Zappa, Marco Antonio ; Bargiggia, Stefano ; Parente, Fabrizio ; Giancarlo Spinzi, Spinzi ; Leoci, Claudio ; Piubello, Walter ; Simone Grillo, Grillo. / Early and delayed complications of polypectomy in a community setting : The SPoC prospective multicentre trial. In: Digestive and Liver Disease. 2016 ; Vol. 48, No. 1. pp. 43-48.
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T2 - The SPoC prospective multicentre trial

AU - Amato, Arnaldo

AU - Radaelli, Franco

AU - Dinelli, Marco

AU - Crosta, Cristiano

AU - Cengia, Gianpaolo

AU - Beretta, Paolo

AU - Devani, Massimo

AU - Lochis, Davide

AU - Manes, Giampiero

AU - Fini, Lucia

AU - Paggi, Silvia

AU - Passoni, Giovanni Rubis

AU - Repici, Alessandro

AU - Redaelli, Alessandro

AU - Renzo Cestari, Cestari

AU - Alberto Prada, Prada

AU - Bernasconi, Giordano

AU - Pallotta, Stefano

AU - Gebbia, Carlotta

AU - Cambareri, Antonio

AU - Rovedatti, Laura

AU - Perego, Maurizio

AU - Viganò, Chiara

AU - Zappa, Marco Antonio

AU - Bargiggia, Stefano

AU - Parente, Fabrizio

AU - Giancarlo Spinzi, Spinzi

AU - Leoci, Claudio

AU - Piubello, Walter

AU - Simone Grillo, Grillo

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Background: Colonoscopic polypectomy is effective in reducing the incidence of and mortality from colorectal cancer, but is not complication-free. Aims: To evaluate the incidence of early and delayed polypectomy complications and factors associated with their occurrence in a community setting. Methods: Web-database collection of patients' and polyp's features in consecutive colonic polypectomies during a 3-month period in 18 endoscopy centres. Results: Data on 5178 polypectomies in 2692 patients (54.3% males, mean age 59 years) were collected. The majority of the polyps were 10 mm: OR 4.35, 95% CI 5.53-7.48) and, inversely, right-sided location (OR 0.58, 95% CI 0.36-0.94) were correlated with bleeding events. The use of antithrombotics was associated with 5-fold increased risk of delayed bleeding. Conclusions: In the community setting, polypectomy was associated with a 1.4% risk of major complications. Polyp size and, inversely, right-sided location were associated with early bleeding; the use of antithrombotics increased the risk of delayed events.

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