TY - JOUR
T1 - Early and delayed complications of polypectomy in a community setting
T2 - The SPoC prospective multicentre trial
AU - Amato, Arnaldo
AU - Radaelli, F.
AU - Dinelli, M.
AU - Crosta, Cristiano
AU - Cengia, G.
AU - Beretta, P.
AU - Devani, M.
AU - Lochis, Davide
AU - Manes, Giampiero
AU - Fini, Lucia
AU - Paggi, S.
AU - Passoni, Giovanni Rubis
AU - Repici, Alessandro
AU - Redaelli, Alessandro
AU - Renzo Cestari, Cestari
AU - Alberto Prada, Prada
AU - Bernasconi, Giordano
AU - Pallotta, S.
AU - Gebbia, Carlotta
AU - Cambareri, Antonio
AU - Rovedatti, Laura
AU - Perego, M.
AU - Viganò, Chiara
AU - Zappa, Marco Antonio
AU - Bargiggia, Stefano
AU - Parente, F.
AU - Giancarlo Spinzi, Spinzi
AU - Leoci, Claudio
AU - Piubello, Walter
AU - Simone Grillo, Grillo
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Background: Colonoscopic polypectomy is effective in reducing the incidence of and mortality from colorectal cancer, but is not complication-free. Aims: To evaluate the incidence of early and delayed polypectomy complications and factors associated with their occurrence in a community setting. Methods: Web-database collection of patients' and polyp's features in consecutive colonic polypectomies during a 3-month period in 18 endoscopy centres. Results: Data on 5178 polypectomies in 2692 patients (54.3% males, mean age 59 years) were collected. The majority of the polyps were 10 mm: OR 4.35, 95% CI 5.53-7.48) and, inversely, right-sided location (OR 0.58, 95% CI 0.36-0.94) were correlated with bleeding events. The use of antithrombotics was associated with 5-fold increased risk of delayed bleeding. Conclusions: In the community setting, polypectomy was associated with a 1.4% risk of major complications. Polyp size and, inversely, right-sided location were associated with early bleeding; the use of antithrombotics increased the risk of delayed events.
AB - Background: Colonoscopic polypectomy is effective in reducing the incidence of and mortality from colorectal cancer, but is not complication-free. Aims: To evaluate the incidence of early and delayed polypectomy complications and factors associated with their occurrence in a community setting. Methods: Web-database collection of patients' and polyp's features in consecutive colonic polypectomies during a 3-month period in 18 endoscopy centres. Results: Data on 5178 polypectomies in 2692 patients (54.3% males, mean age 59 years) were collected. The majority of the polyps were 10 mm: OR 4.35, 95% CI 5.53-7.48) and, inversely, right-sided location (OR 0.58, 95% CI 0.36-0.94) were correlated with bleeding events. The use of antithrombotics was associated with 5-fold increased risk of delayed bleeding. Conclusions: In the community setting, polypectomy was associated with a 1.4% risk of major complications. Polyp size and, inversely, right-sided location were associated with early bleeding; the use of antithrombotics increased the risk of delayed events.
KW - Colonoscopic polypectomy
KW - Polypectomy complications
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U2 - 10.1016/j.dld.2015.09.007
DO - 10.1016/j.dld.2015.09.007
M3 - Article
VL - 48
SP - 43
EP - 48
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 1
ER -