Early and delayed complications of polypectomy in a community setting: The SPoC prospective multicentre trial

Arnaldo Amato, F. Radaelli, M. Dinelli, Cristiano Crosta, G. Cengia, P. Beretta, M. Devani, Davide Lochis, Giampiero Manes, Lucia Fini, S. Paggi, Giovanni Rubis Passoni, Alessandro Repici, Alessandro Redaelli, Cestari Renzo Cestari, Prada Alberto Prada, Giordano Bernasconi, S. Pallotta, Carlotta Gebbia, Antonio CambareriLaura Rovedatti, M. Perego, Chiara Viganò, Marco Antonio Zappa, Stefano Bargiggia, F. Parente, Spinzi Giancarlo Spinzi, Claudio Leoci, Walter Piubello, Grillo Simone Grillo

Research output: Contribution to journalArticlepeer-review


Background: Colonoscopic polypectomy is effective in reducing the incidence of and mortality from colorectal cancer, but is not complication-free. Aims: To evaluate the incidence of early and delayed polypectomy complications and factors associated with their occurrence in a community setting. Methods: Web-database collection of patients' and polyp's features in consecutive colonic polypectomies during a 3-month period in 18 endoscopy centres. Results: Data on 5178 polypectomies in 2692 patients (54.3% males, mean age 59 years) were collected. The majority of the polyps were 10 mm: OR 4.35, 95% CI 5.53-7.48) and, inversely, right-sided location (OR 0.58, 95% CI 0.36-0.94) were correlated with bleeding events. The use of antithrombotics was associated with 5-fold increased risk of delayed bleeding. Conclusions: In the community setting, polypectomy was associated with a 1.4% risk of major complications. Polyp size and, inversely, right-sided location were associated with early bleeding; the use of antithrombotics increased the risk of delayed events.

Original languageEnglish
Pages (from-to)43-48
Number of pages6
JournalDigestive and Liver Disease
Issue number1
Publication statusPublished - Jan 1 2016


  • Colonoscopic polypectomy
  • Polypectomy complications

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology


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