Early and late effects of coronary artery bypass grafting on cardiac haemodynamics during daily physical activities in patients with coronary artery disease

Massimo Imbriaco, Adele Ferro, Giovanni Storto, Teresa Pellegrino, Giacomo Sica, Alberto Cuocolo

Research output: Contribution to journalArticlepeer-review

Abstract

This study investigated the early and late effects of coronary artery bypass grafting (CABG) on left ventricular (LV) function during different physical daily activities in patients with multivessel coronary artery disease (CAD). In ten patients with multivessel CAD, cardiac haemodynamics were assessed during a 6-min walk test and during stair climbing 8±2 days before (study 1) and 15±3 days (study 2) and 120±3 days (study 3) after CABG. LV function was monitored by an ambulatory radionuclide system. In study 1, the walk test induced a significant increase in relative end-diastolic volume (EDV) and end-systolic volume (ESV) and no change in LV ejection fraction as compared to rest. In both study 2 and study 3, EDV increased significantly and ESV was unchanged. As a consequence, LV ejection fraction rose from 48%±8% to 52%±10% and from 48%±7% to 51%±6%, respectively (both P

Original languageEnglish
Pages (from-to)852-856
Number of pages5
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume31
Issue number6
Publication statusPublished - Jun 2004

Keywords

  • Coronary revascularisation
  • Left ventricular function
  • Stress tests

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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