Early bronchial involvement in children with allergic rhinitis

Giorgio Ciprandi, Michele Capasso, Maria Angela Tosca

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Allergic rhinitis (AR) may be frequently associated with asthma or precede it. Bronchial involvement in AR is usually detected by spirometry. Forced expiratory volume in 1 second (FEV 1) is considered a reliable parameter for asthma diagnosis. However, forced expiratory flow at 25-75% (FEF 25-75) could be considered a possible marker of early bronchial involvement in AR; indeed, it has been proposed that FEF 25-75 values 1 value corresponding to impaired FEF 25-75 values. Methods: Eight hundred fifty AR children (555 boys; median age, 10 years) were studied. Spirometry and skin-prick test were performed in all of them. Descriptive statistic and multivariate analysis were considered. Results: Three-hundred (35.3%) patients had FEF 25-75 values 1 values were associated with overt impaired FEF 25-75 values and the cutoff value was 83%. Conclusion: Spirometry should be adequately interpreted in AR patients; indeed, an FEV 1 cutoff value of 83% detects with good efficiency AR children with early bronchial impairment.

Original languageEnglish
JournalAmerican Journal of Rhinology and Allergy
Volume25
Issue number1
DOIs
Publication statusPublished - Jan 2011

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Immunology and Allergy

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