Individuazione precoce e gestione della coronaropatia nel cuore trapiantato: è tempo per una uniformità di approccio?

Translated title of the contribution: Early diagnosis and management of cardiac allograft vasculopathy: is it time for a standardized approach?

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac allograft vasculopathy (CAV) still represents the main cause of long-term graft loss after heart transplantation. Its silent clinical presentation makes an early identification difficult, with relevant implications for a standardized follow-up. Although technological advances have provided sophisticated non-invasive techniques for CAV assessment, intravascular ultrasound in conjunction with coronary angiography is still the gold standard to detect rapidly progressive CAV and to provide prognostic information during follow-up. Current guidelines recommend annual coronary angiography during the first 5 years and every 2 years thereafter. Although commonly performed, coronary angiography has multiple limitations, especially in young patients and in case of chronic kidney disease. This article aims to review the literature about the monitoring of CAV and to propose an ideal and individualized pathway for early diagnosis of CAV in transplanted patients, based on their cardiovascular risk.

Translated title of the contributionEarly diagnosis and management of cardiac allograft vasculopathy: is it time for a standardized approach?
Original languageItalian
Pages (from-to)377-385
Number of pages9
JournalGiornale italiano di cardiologia (2006)
Volume22
Issue number5
DOIs
Publication statusPublished - May 1 2021

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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