Perineal sepsis is a life-threatening complication of acute leukemia. Although conservative management (antibiotics, incision, and drainage, alone or in combination) is considered the criterion standard, it provides an outcome that is not fully satisfactory, with an overall mortality of roughly 30%. This report presents a case series of 4 children who underwent early defunctioning colostomy for the treatment of perineal sepsis during leukemia. This management proved to be successful and allowed prompt reestablishment of chemotherapy, thus improving overall results. Routine application of this aggressive management in these cases will presumably increase overall survival of children with leukemia.
- Ecthyma gangrenosum
- Perineal sepsis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health