Early diverting colostomy for perianal sepsis in children with acute leukemia

Alessio Pini Prato, Elio Castagnola, Concetta Micalizzi, Carlo Dufour, Stefano Avanzini, Luca Pio, Edoardo Guida, Girolamo Mattioli, Vincenzo Jasonni, Nicola Disma, Leila Mameli, Giovanni Montobbio, Piero Buffa

Research output: Contribution to journalArticlepeer-review


Perineal sepsis is a life-threatening complication of acute leukemia. Although conservative management (antibiotics, incision, and drainage, alone or in combination) is considered the criterion standard, it provides an outcome that is not fully satisfactory, with an overall mortality of roughly 30%. This report presents a case series of 4 children who underwent early defunctioning colostomy for the treatment of perineal sepsis during leukemia. This management proved to be successful and allowed prompt reestablishment of chemotherapy, thus improving overall results. Routine application of this aggressive management in these cases will presumably increase overall survival of children with leukemia.

Original languageEnglish
JournalJournal of Pediatric Surgery
Issue number10
Publication statusPublished - Oct 2012


  • Colostomy
  • Ecthyma gangrenosum
  • Laparoscopy
  • Leukemia
  • Perineal sepsis

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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