Early Experience with a Novel Plaque Excision System for the Treatment of Complex Coronary Lesions

Fumiaki Ikeno, Tomoaki Hinohara, Gregory C. Robertson, Mehrdad Rezaee, Paul G. Yock, Bernhard Reimers, Antonio Colombo, Eberhard Grube, John B. Simpson

Research output: Contribution to journalArticlepeer-review

Abstract

The use of directional coronary atherectomy (DCA) in current practice has been limited. The SilverHawk System is a newly developed plaque excision device that aims to overcome the drawbacks of prior DCA platforms. The device was evaluated in a porcine coronary model and in a series of patients. Procedural variables along with outcomes were reviewed. Quantitative angiography (QCA) was performed and excised tissue fragments were weighed and examined histologically. In porcine cases, pretreatment MLD increased from 0.51 ± 0.26 to 2.36 ± 0.59 mm postdebulking and 19.9 ± 7.6 mg of tissue was retrieved. In human cases, pretreatment MLD increased from 0.8 ± 0.4 to 2.2 ± 0.5 mm postdebulking and 15.2 ± 7.8 mg of tissue was retrieved without complications. These data show that the SilverHawk System may offer significant utility in treating a wide variety of complex coronary lesions.

Original languageEnglish
Pages (from-to)35-43
Number of pages9
JournalCatheterization and Cardiovascular Interventions
Volume61
Issue number1
DOIs
Publication statusPublished - Jan 2004

Keywords

  • Catheter device
  • Coronary artery disease
  • Debulking
  • Percutaneous transluminal angioplasty

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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