Early gallbladder carcinoma: A single-center experience

Vincenzo Cangemi, Enrico Fiori, Cristina Picchi, Alessandro De Cesare, Roberto Cangemi, Gaspare Galati, Patrizia Volpino

Research output: Contribution to journalArticlepeer-review


Aims and background: Controversy continues regarding the best surgical treatment for early gallbladder carcinoma defined as a tumor confined to the mucosa (pT1a) or to the muscularis propria (pT1b) according to the TNM classification. This study evaluates the effectiveness of different surgical approaches in patients with early gallbladder carcinoma in terms of longterm survival. Materials and methods: From 1980 to 2001,175 patients with gallbladder carcinoma were admitted to our department. Fifteen of them underwent resections for early gallbladder carcinoma: 4 patients for pT1a tumors and 11 patients for pT1b tumors. All patients with pT1a tumors and 8 patients with pT1b tumors underwent simple cholecystectomy. The remaining 3 patients with pT1b tumors underwent extended cholecystectomy. Results: The 5-10 year cumulative survival rate was 100% for patients with pT1a tumors, 37.5% for patients with pT1b tumors who underwent simple cholecystectomy, and 100% for patients with pT1b tumors who underwent extended cholecystectomy. Conclusions: Simple cholecystectomy is the appropriate treatment for patients with pT1a tumors, whereas patients with pT1b tumors require an extended cholecystectomy.

Original languageEnglish
Pages (from-to)487-490
Number of pages4
Issue number6
Publication statusPublished - Nov 2006


  • Early gallbladder carcinoma
  • Extended cholecystectomy
  • Simple cholecystectomy

ASJC Scopus subject areas

  • Cancer Research


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