Early renal lesions are described in experimental lead poisoning obtained with relatively low doses of lead (10 and 1000 γ). Such alterations, consisting of glomerular and tubular changes, are attributed partly to renal hypoxia and partly to increased potassium excretion. As a support to this latter mechanism the authors found a decreased mucopolysaccharide exudation in kidneys of animals treated with spironolactone in addition to lead.
|Translated title of the contribution||Early histological and histochemical changes in the kidney in experimental lead poisoning|
|Number of pages||7|
|Journal||Medicina del Lavoro|
|Publication status||Published - 1972|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health