Early lung retransplantation in a patient affected by cystic fibrosis correlated with donor cause of death

A case report

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The relationship between donor cause of death and lung transplantation outcomes remains unclear. We report a case of lung transplantation in a young patient affected by cystic fibrosis. Immediately after lung reperfusion a pulmonary hypertension was observed that was intractable with maximal medical therapy requiring surgical resection of the left lower lobe which became congested after a few days. The donor had died from suicidal hanging; the authors attributed the posttransplantation pulmonary hypertension which is an uncommon form of primary graft dysfunction to this cause of death. The patient was treated with early bilateral lung retransplantation which required a long, troublesome hospital stay. In conclusion, the authors warn against the use of lungs from donors who die due to hanging even when the gas exchanges were ideal.

Original languageEnglish
Pages (from-to)2041-2042
Number of pages2
JournalTransplantation Proceedings
Volume44
Issue number7
DOIs
Publication statusPublished - Sep 2012

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Cystic Fibrosis
Cause of Death
Lung Transplantation
Tissue Donors
Pulmonary Hypertension
Lung
Primary Graft Dysfunction
Reperfusion
Length of Stay
Gases
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

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title = "Early lung retransplantation in a patient affected by cystic fibrosis correlated with donor cause of death: A case report",
abstract = "The relationship between donor cause of death and lung transplantation outcomes remains unclear. We report a case of lung transplantation in a young patient affected by cystic fibrosis. Immediately after lung reperfusion a pulmonary hypertension was observed that was intractable with maximal medical therapy requiring surgical resection of the left lower lobe which became congested after a few days. The donor had died from suicidal hanging; the authors attributed the posttransplantation pulmonary hypertension which is an uncommon form of primary graft dysfunction to this cause of death. The patient was treated with early bilateral lung retransplantation which required a long, troublesome hospital stay. In conclusion, the authors warn against the use of lungs from donors who die due to hanging even when the gas exchanges were ideal.",
author = "D. Tosi and P. Mendogni and L. Rosso and A. Palleschi and N. Filippi and M. Reda and L. Santambrogio and M. Nosotti",
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AU - Tosi, D.

AU - Mendogni, P.

AU - Rosso, L.

AU - Palleschi, A.

AU - Filippi, N.

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AU - Santambrogio, L.

AU - Nosotti, M.

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AB - The relationship between donor cause of death and lung transplantation outcomes remains unclear. We report a case of lung transplantation in a young patient affected by cystic fibrosis. Immediately after lung reperfusion a pulmonary hypertension was observed that was intractable with maximal medical therapy requiring surgical resection of the left lower lobe which became congested after a few days. The donor had died from suicidal hanging; the authors attributed the posttransplantation pulmonary hypertension which is an uncommon form of primary graft dysfunction to this cause of death. The patient was treated with early bilateral lung retransplantation which required a long, troublesome hospital stay. In conclusion, the authors warn against the use of lungs from donors who die due to hanging even when the gas exchanges were ideal.

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