Early macronutrient intake and overweight at five years of age

S. Scaglioni, C. Agostoni, R. De Notaris, G. Radaelli, N. Radice, M. Valenti, M. Giovannini, E. Riva

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: To examine the influence of the macronutrient intake in early life on the development of overweight in children. DESIGN AND SUBJECTS: An ongoing longitudinal study including 147 randomized healthy children followed up from birth. MEASUREMENTS: Anthropometric parameters were measured at birth, 1 and 5 y of age. Dietary habits at the age of 1 and 5 were assessed by age-adjusted food-frequency questionnaires and 24 h recalls. Parents' body mass index (BMI) was also recorded. RESULTS: Parental overweight was observed for 51% children. The prevalence of overweight at the age of 5 y was higher in children with than without parental overweight (37.3% vs 8.3%, P <0.0001). Five-year old overweight children had a higher percentage intake of proteins at the age of ly than non overweight children (22% vs 20%, P = 0.024) and lower intake of carbohydrates (44% vs 47%, P = 0.031). Multiple logistic analysis confirmed that protein intake at ly of age was associated with overweight at 5 y (P = 0.05). In children born from overweight mothers, prevalence of overweight at the age of 5 y tended to be higher in bottle-fed than in breast-fed ones (62.5% vs 23.3%, P = 0.08). CONCLUSION: Parental overweight is a major risk factor for childhood overweight in the first years of life, but an early high protein intake may also influence the development of adiposity.

Original languageEnglish
Pages (from-to)777-781
Number of pages5
JournalInternational Journal of Obesity
Issue number6
Publication statusPublished - 2000


  • Body mass index
  • Childhood obesity
  • Macronutrient intake

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Food Science
  • Endocrinology, Diabetes and Metabolism


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