TY - JOUR
T1 - Early palliative care in haematological patients: A systematic literature review
AU - Tanzi, Silvia
AU - Venturelli, Francesco
AU - Luminari, Stefano
AU - Merlo, Franco Domenico
AU - Braglia, Luca
AU - Bassi, Chiara
AU - Costantini, Massimo
N1 - Publisher Copyright:
©
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Background Early palliative care together with standard haematological care for advanced patients is needed worldwide. Little is known about its effect. The aim of the review is to synthesise the evidence on the impact of early palliative care on haematologic cancer patients' quality of life and resource use. Patients and methods A systematic review was conducted. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematological or oncohaematological patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility. Results A total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the six non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions. Conclusions Studies on early palliative care and patients with haematological cancer are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardisation of collected outcomes is required. PROSPERO registration number CRD42020141322.
AB - Background Early palliative care together with standard haematological care for advanced patients is needed worldwide. Little is known about its effect. The aim of the review is to synthesise the evidence on the impact of early palliative care on haematologic cancer patients' quality of life and resource use. Patients and methods A systematic review was conducted. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematological or oncohaematological patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility. Results A total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the six non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions. Conclusions Studies on early palliative care and patients with haematological cancer are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardisation of collected outcomes is required. PROSPERO registration number CRD42020141322.
KW - cancer
KW - haematological disease
UR - http://www.scopus.com/inward/record.url?scp=85093977357&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85093977357&partnerID=8YFLogxK
U2 - 10.1136/bmjspcare-2020-002386
DO - 10.1136/bmjspcare-2020-002386
M3 - Review article
C2 - 33055091
AN - SCOPUS:85093977357
VL - 10
SP - 395
EP - 403
JO - BMJ Supportive and Palliative Care
JF - BMJ Supportive and Palliative Care
SN - 2045-435X
IS - 4
ER -