Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 669-675 |
| Number of pages | 7 |
| Journal | Journal of Urology |
| Volume | 197 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2017 |
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Early Postoperative Radiotherapy is Associated with Worse Functional Outcomes in Patients with Prostate Cancer. / Zaffuto, E; Gandaglia, G; Fossati, Nicola; Dell'Oglio, P; Moschini, M; Cucchiara, V; Suardi, N; Mirone, Vincenzo; Bandini, M; Shariat, SF; Karakiewicz, PI; Montorsi, F; Briganti, A.
In: Journal of Urology, Vol. 197, No. 3, 2017, p. 669-675.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Early Postoperative Radiotherapy is Associated with Worse Functional Outcomes in Patients with Prostate Cancer
AU - Zaffuto, E
AU - Gandaglia, G
AU - Fossati, Nicola
AU - Dell'Oglio, P
AU - Moschini, M
AU - Cucchiara, V
AU - Suardi, N
AU - Mirone, Vincenzo
AU - Bandini, M
AU - Shariat, SF
AU - Karakiewicz, PI
AU - Montorsi, F
AU - Briganti, A
PY - 2017
Y1 - 2017
N2 - Purpose The effect of time between radical prostatectomy and radiation therapy on postoperative functional outcomes is still unclear in patients with surgically managed prostate cancer. We hypothesized that a shorter time between radical prostatectomy and radiotherapy might be associated with worse functional recovery rates after radical prostatectomy. Materials and Methods We retrospectively evaluated 2,190 patients treated with radical prostatectomy and stratified according to radiotherapy schedule (adjuvant radiotherapy, salvage radiotherapy, no radiotherapy). We examined recovery rates for erectile function and urinary function according to adjuvant radiotherapy, salvage radiotherapy and no radiotherapy, and according to time from surgery to radiotherapy. Cox regression analyses were used to evaluate the impact of these predictors on functional outcomes. Results Median followup was 48 months. The 3-year erectile function recovery rates were 35.0%, 29.0% and 11.6% in patients who received no radiotherapy, salvage radiotherapy and adjuvant radiotherapy, respectively (p
AB - Purpose The effect of time between radical prostatectomy and radiation therapy on postoperative functional outcomes is still unclear in patients with surgically managed prostate cancer. We hypothesized that a shorter time between radical prostatectomy and radiotherapy might be associated with worse functional recovery rates after radical prostatectomy. Materials and Methods We retrospectively evaluated 2,190 patients treated with radical prostatectomy and stratified according to radiotherapy schedule (adjuvant radiotherapy, salvage radiotherapy, no radiotherapy). We examined recovery rates for erectile function and urinary function according to adjuvant radiotherapy, salvage radiotherapy and no radiotherapy, and according to time from surgery to radiotherapy. Cox regression analyses were used to evaluate the impact of these predictors on functional outcomes. Results Median followup was 48 months. The 3-year erectile function recovery rates were 35.0%, 29.0% and 11.6% in patients who received no radiotherapy, salvage radiotherapy and adjuvant radiotherapy, respectively (p
U2 - 10.1016/j.juro.2016.09.079
DO - 10.1016/j.juro.2016.09.079
M3 - Article
VL - 197
SP - 669
EP - 675
JO - Journal of Urology
JF - Journal of Urology
SN - 0022-5347
IS - 3
ER -