TY - JOUR
T1 - Early pulmonary function and mid-term outcome in lung transplantation after ex-vivo lung perfusion - a single-center, retrospective, observational, cohort study.
T2 - Transplant international : official journal of the European Society for Organ Transplantation
AU - Fumagalli, Jacopo
AU - Rosso, Lorenzo
AU - Gori, Francesca
AU - Morlacchi, Letizia Corinna
AU - Rossetti, Valeria
AU - Tarsia, Paolo
AU - Blasi, Francesco
AU - Righi, Ilaria
AU - Mendogni, Paolo
AU - Palleschi, Alessandro
AU - Tosi, Davide
AU - Bonitta, Gianluca
AU - Nosotti, Mario
AU - Benazzi, Elena
AU - Scaravilli, Vittorio
AU - Valenza, Franco
AU - Grasselli, Giacomo
AU - Zanella, Alberto
PY - 2020
Y1 - 2020
N2 - Outcomes after transplantation of lungs (LuTX) treated with ex-vivo lung perfusion (EVLP) are debated. In a single-center 8 years of retrospective analysis, we compared: donors' and recipients' characteristics, gas exchange and lung mechanics at ICU admission, 3, 6, and 12 months, and patients' survival of LuTX from standard donors compared with EVLP-treated grafts. A total of 193 LuTX were performed. Thirty-one LuTX, out of 50 EVLP procedures, were carried out: 7 from nonheart beating and 24 from extended criteria brain-dead donors. Recipients' characteristics were similar. At ICU admission, compared with standard donors, EVLP patients had worse PaO(2) /FiO(2) [276 (206; 374) vs. 204 (133; 245) mmHg, P
AB - Outcomes after transplantation of lungs (LuTX) treated with ex-vivo lung perfusion (EVLP) are debated. In a single-center 8 years of retrospective analysis, we compared: donors' and recipients' characteristics, gas exchange and lung mechanics at ICU admission, 3, 6, and 12 months, and patients' survival of LuTX from standard donors compared with EVLP-treated grafts. A total of 193 LuTX were performed. Thirty-one LuTX, out of 50 EVLP procedures, were carried out: 7 from nonheart beating and 24 from extended criteria brain-dead donors. Recipients' characteristics were similar. At ICU admission, compared with standard donors, EVLP patients had worse PaO(2) /FiO(2) [276 (206; 374) vs. 204 (133; 245) mmHg, P
KW - ex-vivo lung perfusion
KW - lung transplantation
U2 - 10.1111/tri.13606
DO - 10.1111/tri.13606
M3 - Article
VL - 33
SP - 773
EP - 785
JO - Transplant International
JF - Transplant International
SN - 0934-0874
IS - 7
ER -