Early Renal Abnormalities as an Indicator of Cardiovascular Risk in Type 2 Diabetes

Francesca Viazzi, Barbara Bonino, Elena Ratto, Salvatore De Cosmo, Roberto Pontremoli

Research output: Contribution to journalArticle

Abstract

Accurate assessment of cardiovascular (CV) risk is a prerequisite for devising effective therapeutic strategies in patients with type 2 diabetes (T2DM) as it allows to refine prognosis and treatment targets as well as the cost-benefit ratio for specific pharmacological interventions. The presence of subclinical vascular organ damage plays a well known role in determining overall risk and a wider use of low cost, easy to perform diagnostic tools to stratify CV risk is very much needed. Besides their well known prognostic value for progression to end stage renal disease (ESRD), subclinical renal abnormalities such as microalbuminuria and/or a slight reduction in estimation of glomerular filtration rate (eGFR), have been shown to be powerful, independent predictors of CV diseases in patients with T2DM. Through the combined evaluation of these two biomarkers of chronic kidney disease (CKD), clinicians can usefully and reliably get a perspective on global and CV outcome of their diabetic patients.

Original languageEnglish
Pages (from-to)257-260
Number of pages4
JournalHigh Blood Pressure and Cardiovascular Prevention
Volume21
Issue number4
DOIs
Publication statusPublished - Nov 20 2014

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Keywords

  • Cardiovascular risk
  • Chronic kidney disease
  • Diabetes
  • Glomerular filtration rate
  • Microalbuminuria

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Medicine(all)

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