Abstract
Previous findings demonstrated an altered pattern of amyloid precursor protein (APP) forms in platelets of Alzheimer disease (AD) patients, compared both with healthy control subjects or patients with non-Alzheimer-type dementia. The present study aims to evaluate whether platelet APP form ratio (APPr) is altered in patients with early stage AD. We selected 40 patients with early stage AD and 40 age-matched healthy controls. Compared with controls (mean±SD=0.91±0.3), mean APPr was decreased in AD (mean±SD=0.46±0.26, p
Original language | English |
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Pages (from-to) | 207-210 |
Number of pages | 4 |
Journal | Neurological Sciences |
Volume | 23 |
Issue number | 5 |
DOIs | |
Publication status | Published - Dec 2002 |
Keywords
- Amyloid precursor protein
- Diagnosis
- Early stage Alzheimer disease
- Platelets
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology