Early structured surgical management plan for neonates with short bowel syndrome may improve outcomes

S. J. Wood, B. Khalil, F. Fusaro, S. E. Folaranmi, S. A. Sparks, A. Morabito

Research output: Contribution to journalArticle

Abstract

Background: In children with short bowel syndrome, maximal adaptation of the bowel after extensive resection is thought to occur during the first 2 years of life. The aim of the present study was to review children with short bowel syndrome from two intestinal rehabilitation centers, comparing those undergoing lengthening procedures 365 days of age (late). Methods: Retrospective data collection was performed from January 2004 to December 2010 in Manchester, UK, and from December 2006 to December 2010 in Brussels, Belgium. Both medical centers follow a similar intestinal rehabilitation program (IRP). Data collected included population demographics, bowel length preoperatively and postoperatively, age at operation, parenteral nutrition (PN), central access, and complications. Results: Complete data were available for eight children who underwent lengthening surgery at 365 days of age. Diagnoses were similar. Groups were matched for gestation and birthweight, with no statistical difference in preoperative and postoperative bowel lengths. The mean duration of PN postoperatively was 378 days in the early cohort and 589 days in the late cohort. This trended toward statistical significance (p = 0.071). Full enteral autonomy was achieved at 17 months (early) and 59 months (late) (p = 0.01). Patients in the early group required fewer central lines than those operated on later (p = 0.035). Conclusions: Enrolling children into an IRP involving early (

Original languageEnglish
Pages (from-to)1714-1717
Number of pages4
JournalWorld Journal of Surgery
Volume37
Issue number7
DOIs
Publication statusPublished - Jul 2013

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

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