Echocardiographic determinants of mortality in patients >67 years of age with chronic heart failure

Viorel G. Florea, Michael Y. Henein, Mariantonietta Cicoira, Stefan D. Anker, Wolfram Doehner, Piotr Ponikowski, Darrel P. Francis, Derek G. Gibson, Andrew J S Coats

Research output: Contribution to journalArticle

Abstract

This study sought to assess the prognostic significance of echocardiographic measurements of left and right ventricular dimensions and function in patients >67 years of age with chronic congestive heart failure (CHF). This is a retrospective follow-up of elderly patients who underwent an echocardiography in the tertiary cardiac center. A total of 185 patients (131 men) aged ≥68 years (mean ± SD 75 ± 5) with CHF were enrolled into the study. After undergoing a detailed echocardiographic examination, all patients were followed-up for a median of 20 months (interquartile range 9 to 36). During the follow-up period 54 patients (29%) died. Left ventricular (LV) M-mode isovolumic relaxation time (IVRT), end-diastolic and end-systolic diameters, fractional shortening and mass, transmitral E:A ratio, and left atrial dimension, as well as New York Heart Association class and the age were found by Cox proportional-hazards univariate analyses to predict the outcome in these patients (all p 30 ms had a better prognosis at 3 years (cumulative survival 78% [95% confidence interval 65% to 91%]) than those with LV IVRT ≤30 ms (survival 52% [95% confidence interval 37% to 68%]). Measurements of LV performance, especially those obtained during diastole, are significantly related to prognosis in patients >67 years of age with CHF. LV M-mode IVRT is among the most important independent predictors of outcome in this population. Copyright (C) 2000 Excerpta Medica Inc.

Original languageEnglish
Pages (from-to)158-161
Number of pages4
JournalThe American Journal of Cardiology
Volume86
Issue number2
DOIs
Publication statusPublished - Jul 2000

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Heart Failure
Mortality
Confidence Intervals
Right Ventricular Function
Diastole
Survival
Echocardiography
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Florea, V. G., Henein, M. Y., Cicoira, M., Anker, S. D., Doehner, W., Ponikowski, P., ... Coats, A. J. S. (2000). Echocardiographic determinants of mortality in patients >67 years of age with chronic heart failure. The American Journal of Cardiology, 86(2), 158-161. https://doi.org/10.1016/S0002-9149(00)00853-5

Echocardiographic determinants of mortality in patients >67 years of age with chronic heart failure. / Florea, Viorel G.; Henein, Michael Y.; Cicoira, Mariantonietta; Anker, Stefan D.; Doehner, Wolfram; Ponikowski, Piotr; Francis, Darrel P.; Gibson, Derek G.; Coats, Andrew J S.

In: The American Journal of Cardiology, Vol. 86, No. 2, 07.2000, p. 158-161.

Research output: Contribution to journalArticle

Florea, VG, Henein, MY, Cicoira, M, Anker, SD, Doehner, W, Ponikowski, P, Francis, DP, Gibson, DG & Coats, AJS 2000, 'Echocardiographic determinants of mortality in patients >67 years of age with chronic heart failure', The American Journal of Cardiology, vol. 86, no. 2, pp. 158-161. https://doi.org/10.1016/S0002-9149(00)00853-5
Florea, Viorel G. ; Henein, Michael Y. ; Cicoira, Mariantonietta ; Anker, Stefan D. ; Doehner, Wolfram ; Ponikowski, Piotr ; Francis, Darrel P. ; Gibson, Derek G. ; Coats, Andrew J S. / Echocardiographic determinants of mortality in patients >67 years of age with chronic heart failure. In: The American Journal of Cardiology. 2000 ; Vol. 86, No. 2. pp. 158-161.
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