Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis

Enrico Vizzardi, Ilaria Cavazzana, Chiara Bazzani, Natalia Pezzali, Angela Ceribelli, Ivano Bonadei, Franco Franceschini, Antonio D'Aloia, Marco Metra, Angela Tincani, Livio Dei Cas

Research output: Contribution to journalArticle

Abstract

Background: Rheumatoid arthritis (RA) is associated with increased mortality and morbidity because of accelerated atherosclerosis. The study assessed the prevalence of left and right ventricle diastolic and systolic dysfunction in outpatients with RA. Methods: The study included 93 outpatients with RA. In all patients and control group, echocardiographic conventional and tissue Doppler (TDI) studies were conducted. Results: In the group of RA patients, we found high prevalence of left ventricular systolic and diastolic dysfunction and right diastolic dysfunction compared with controls (13.5% vs 5.5 %, 76.3% vs 48.8% and 41.9% vs 6.6%, respectively; P <0.001). Rheumatoid arthritis patients and controls showed significant differences about mitral, tricuspid, and pulmonary flow velocity curves; tissue Doppler curves of the lateral and the septal myocardial walls of the left ventricle; and basal myocardial free wall of the right ventricle. There were not any correlations between inflammatory and functional disease parameters and variables of systolic and diastolic function. Conclusions: Our study shows a high prevalence of left ventricular systolic and diastolic dysfunction in a population of outpatients affected by rheumatoid arthritis.

Original languageEnglish
Pages (from-to)1204-1208
Number of pages5
JournalJournal of Investigative Medicine
Volume60
Issue number8
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Rheumatoid Arthritis
Heart Ventricles
Tissue
Outpatients
Flow velocity
Atherosclerosis
Cross-Sectional Studies
Morbidity
Lung
Control Groups
Mortality
Population

Keywords

  • Diastolic dysfunction
  • Echocardiography
  • Left ventricular dysfunction
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis. / Vizzardi, Enrico; Cavazzana, Ilaria; Bazzani, Chiara; Pezzali, Natalia; Ceribelli, Angela; Bonadei, Ivano; Franceschini, Franco; D'Aloia, Antonio; Metra, Marco; Tincani, Angela; Cas, Livio Dei.

In: Journal of Investigative Medicine, Vol. 60, No. 8, 12.2012, p. 1204-1208.

Research output: Contribution to journalArticle

Vizzardi, E, Cavazzana, I, Bazzani, C, Pezzali, N, Ceribelli, A, Bonadei, I, Franceschini, F, D'Aloia, A, Metra, M, Tincani, A & Cas, LD 2012, 'Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis', Journal of Investigative Medicine, vol. 60, no. 8, pp. 1204-1208. https://doi.org/10.231/JIM.0b013e3182746a83
Vizzardi, Enrico ; Cavazzana, Ilaria ; Bazzani, Chiara ; Pezzali, Natalia ; Ceribelli, Angela ; Bonadei, Ivano ; Franceschini, Franco ; D'Aloia, Antonio ; Metra, Marco ; Tincani, Angela ; Cas, Livio Dei. / Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis. In: Journal of Investigative Medicine. 2012 ; Vol. 60, No. 8. pp. 1204-1208.
@article{aee36c2861b5455d864874263cabf671,
title = "Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis",
abstract = "Background: Rheumatoid arthritis (RA) is associated with increased mortality and morbidity because of accelerated atherosclerosis. The study assessed the prevalence of left and right ventricle diastolic and systolic dysfunction in outpatients with RA. Methods: The study included 93 outpatients with RA. In all patients and control group, echocardiographic conventional and tissue Doppler (TDI) studies were conducted. Results: In the group of RA patients, we found high prevalence of left ventricular systolic and diastolic dysfunction and right diastolic dysfunction compared with controls (13.5{\%} vs 5.5 {\%}, 76.3{\%} vs 48.8{\%} and 41.9{\%} vs 6.6{\%}, respectively; P <0.001). Rheumatoid arthritis patients and controls showed significant differences about mitral, tricuspid, and pulmonary flow velocity curves; tissue Doppler curves of the lateral and the septal myocardial walls of the left ventricle; and basal myocardial free wall of the right ventricle. There were not any correlations between inflammatory and functional disease parameters and variables of systolic and diastolic function. Conclusions: Our study shows a high prevalence of left ventricular systolic and diastolic dysfunction in a population of outpatients affected by rheumatoid arthritis.",
keywords = "Diastolic dysfunction, Echocardiography, Left ventricular dysfunction, Rheumatoid arthritis",
author = "Enrico Vizzardi and Ilaria Cavazzana and Chiara Bazzani and Natalia Pezzali and Angela Ceribelli and Ivano Bonadei and Franco Franceschini and Antonio D'Aloia and Marco Metra and Angela Tincani and Cas, {Livio Dei}",
year = "2012",
month = "12",
doi = "10.231/JIM.0b013e3182746a83",
language = "English",
volume = "60",
pages = "1204--1208",
journal = "Journal of Investigative Medicine",
issn = "1081-5589",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

TY - JOUR

T1 - Echocardiographic evaluation of asymptomatic patients affected by rheumatoid arthritis

AU - Vizzardi, Enrico

AU - Cavazzana, Ilaria

AU - Bazzani, Chiara

AU - Pezzali, Natalia

AU - Ceribelli, Angela

AU - Bonadei, Ivano

AU - Franceschini, Franco

AU - D'Aloia, Antonio

AU - Metra, Marco

AU - Tincani, Angela

AU - Cas, Livio Dei

PY - 2012/12

Y1 - 2012/12

N2 - Background: Rheumatoid arthritis (RA) is associated with increased mortality and morbidity because of accelerated atherosclerosis. The study assessed the prevalence of left and right ventricle diastolic and systolic dysfunction in outpatients with RA. Methods: The study included 93 outpatients with RA. In all patients and control group, echocardiographic conventional and tissue Doppler (TDI) studies were conducted. Results: In the group of RA patients, we found high prevalence of left ventricular systolic and diastolic dysfunction and right diastolic dysfunction compared with controls (13.5% vs 5.5 %, 76.3% vs 48.8% and 41.9% vs 6.6%, respectively; P <0.001). Rheumatoid arthritis patients and controls showed significant differences about mitral, tricuspid, and pulmonary flow velocity curves; tissue Doppler curves of the lateral and the septal myocardial walls of the left ventricle; and basal myocardial free wall of the right ventricle. There were not any correlations between inflammatory and functional disease parameters and variables of systolic and diastolic function. Conclusions: Our study shows a high prevalence of left ventricular systolic and diastolic dysfunction in a population of outpatients affected by rheumatoid arthritis.

AB - Background: Rheumatoid arthritis (RA) is associated with increased mortality and morbidity because of accelerated atherosclerosis. The study assessed the prevalence of left and right ventricle diastolic and systolic dysfunction in outpatients with RA. Methods: The study included 93 outpatients with RA. In all patients and control group, echocardiographic conventional and tissue Doppler (TDI) studies were conducted. Results: In the group of RA patients, we found high prevalence of left ventricular systolic and diastolic dysfunction and right diastolic dysfunction compared with controls (13.5% vs 5.5 %, 76.3% vs 48.8% and 41.9% vs 6.6%, respectively; P <0.001). Rheumatoid arthritis patients and controls showed significant differences about mitral, tricuspid, and pulmonary flow velocity curves; tissue Doppler curves of the lateral and the septal myocardial walls of the left ventricle; and basal myocardial free wall of the right ventricle. There were not any correlations between inflammatory and functional disease parameters and variables of systolic and diastolic function. Conclusions: Our study shows a high prevalence of left ventricular systolic and diastolic dysfunction in a population of outpatients affected by rheumatoid arthritis.

KW - Diastolic dysfunction

KW - Echocardiography

KW - Left ventricular dysfunction

KW - Rheumatoid arthritis

UR - http://www.scopus.com/inward/record.url?scp=84873635694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873635694&partnerID=8YFLogxK

U2 - 10.231/JIM.0b013e3182746a83

DO - 10.231/JIM.0b013e3182746a83

M3 - Article

C2 - 23111649

VL - 60

SP - 1204

EP - 1208

JO - Journal of Investigative Medicine

JF - Journal of Investigative Medicine

SN - 1081-5589

IS - 8

ER -