Economic evaluation of sublingual immunotherapy: an analysis of literature.

G. Ciprandi, F. Agostinis, S. Amoroso, R. Ariano, A. Barbato, M. Bassi, G. Cadario, P. Campi, F. Cardinale, C. Romano, C. Incorvaia, R. Danneo, S. Dal Bo, M. Di Gioacchino, A. Fiocchi, M. Galimberti, E. Galli, M. Giovannini, S. La Grutta, Carlo LombardiF. Marcucci, G. L. Marseglia, F. Mastrandrea, M. Minelli, E. Nettis, E. Novembre, C. Ortolani, G. Pajno, P. P. Piras, G. Passalacqua, G. Patriarca, S. Pucci, O. Quercia, A. Romano, D. Schiavino, M. Sforza, M. A. Tosca, S. Tripodi, M. Zambito, P. Puccinelli, F. Frati

Research output: Contribution to journalArticle


Allergic rhinitis and asthma constitute a global health problem because of their very high prevalence and the consequent burden of disease, concerning medical and economical issues. Among the treatments of allergy, specific immunotherapy has the capacity to favourably alter the natural history of the disease both during and after its performance and thus to reduce the direct and indirect costs of allergic rhinitis and asthma. A number of studies reported such cost reduction for traditional, subcutaneous immunotherapy and recent data demonstrate that also sublingual immunotherapy (SLIT) is associated to economic advantages and/or monetary savings, specifically in terms of reduction of disease economic burden. Only few formal economic assessments of SLIT have been carried out so far, this article will present and discuss the published studies addressed to this issue. The data obtained, although the number of studies is still limited, provide preliminary evidence supporting a SLIT effect on sparing costs for respiratory allergy.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalEuropean Annals of Allergy and Clinical Immunology
Volume39 Spec No
Publication statusPublished - 2007


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ciprandi, G., Agostinis, F., Amoroso, S., Ariano, R., Barbato, A., Bassi, M., Cadario, G., Campi, P., Cardinale, F., Romano, C., Incorvaia, C., Danneo, R., Dal Bo, S., Di Gioacchino, M., Fiocchi, A., Galimberti, M., Galli, E., Giovannini, M., La Grutta, S., ... Frati, F. (2007). Economic evaluation of sublingual immunotherapy: an analysis of literature. European Annals of Allergy and Clinical Immunology, 39 Spec No, 21-26.