Ectopic ACTH syndrome due to occult bronchial carcinoid

Salvatore Maria Corsello, Danilo Fintini, Rosa Maria Lovicu, Rosa Maria Paragliola, Vittoria Rufini, Giovanni Simonetti, Alfredo Pontecorvi

Research output: Contribution to journalArticle

Abstract

Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed.

Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalClinical Nuclear Medicine
Volume34
Issue number7
DOIs
Publication statusPublished - Jul 2009

Keywords

  • 111 In-Octreoscan
  • Bilateral inferior petrosal sinus sampling
  • Bronchial carcinoid
  • Ectopic Cushing syndrome
  • SPECT-CT
  • Virtual bronchoscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Corsello, S. M., Fintini, D., Lovicu, R. M., Paragliola, R. M., Rufini, V., Simonetti, G., & Pontecorvi, A. (2009). Ectopic ACTH syndrome due to occult bronchial carcinoid. Clinical Nuclear Medicine, 34(7), 459-461. https://doi.org/10.1097/RLU.0b013e3181a7d22e