Ectopic ACTH syndrome due to occult bronchial carcinoid

Salvatore Maria Corsello, Danilo Fintini, Rosa Maria Lovicu, Rosa Maria Paragliola, Vittoria Rufini, Giovanni Simonetti, Alfredo Pontecorvi

Research output: Contribution to journalArticlepeer-review

Abstract

Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed.

Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalClinical Nuclear Medicine
Volume34
Issue number7
DOIs
Publication statusPublished - Jul 2009

Keywords

  • 111 In-Octreoscan
  • Bilateral inferior petrosal sinus sampling
  • Bronchial carcinoid
  • Ectopic Cushing syndrome
  • SPECT-CT
  • Virtual bronchoscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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