Ectopic ACTH syndrome due to occult bronchial carcinoid

Salvatore Maria Corsello; Danilo Fintini; Rosa Maria Lovicu; Rosa Maria Paragliola; Vittoria Rufini; Giovanni Simonetti; Alfredo Pontecorvi

doi:10.1097/RLU.0b013e3181a7d22e

Ectopic ACTH syndrome due to occult bronchial carcinoid

Salvatore Maria Corsello, Danilo Fintini, Rosa Maria Lovicu, Rosa Maria Paragliola, Vittoria Rufini, Giovanni Simonetti, Alfredo Pontecorvi

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed.

Original language	English
Pages (from-to)	459-461
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	34
Issue number	7
DOIs	https://doi.org/10.1097/RLU.0b013e3181a7d22e
Publication status	Published - Jul 2009

Keywords

111 In-Octreoscan
Bilateral inferior petrosal sinus sampling
Bronchial carcinoid
Ectopic Cushing syndrome
SPECT-CT
Virtual bronchoscopy

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0b013e3181a7d22e

Cite this

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title = "Ectopic ACTH syndrome due to occult bronchial carcinoid",

abstract = "Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome. We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion.Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid. Successful surgery was then performed.",

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AU - Corsello, Salvatore Maria

AU - Fintini, Danilo

AU - Lovicu, Rosa Maria

AU - Paragliola, Rosa Maria

AU - Rufini, Vittoria

AU - Simonetti, Giovanni

AU - Pontecorvi, Alfredo

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Ectopic ACTH syndrome due to occult bronchial carcinoid

Abstract

Keywords

ASJC Scopus subject areas

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