Herein we describe a rare case of neuroglial heterotopia (ectopic mature cerebral tissue) incidentally detected by F-FDG PET/CT. A 52-year-old female patient underwent F-FDG PET/CT for metabolic characterization of a left pulmonary nodule. F-FDG PET/CT revealed increased radiopharmaceutical uptake corresponding to the pulmonary nodule pathologically described as adenocarcinoma. Furthermore, an area of increased F-FDG uptake corresponding to a lesion in the left nasal cavity was detected. Endoscopic biopsy of the nasal lesion showed the presence of ectopic mature cerebral tissue suggesting the presence of neuroglial heterotopia.
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