Studio di correlazione EEG e doppler transcranico con valutazione della vasoreattività cerebrale in pazienti sincopali e controlli sani

Neurally-mediated syncope is one of the most common causes of transient loss of consciousness, particularly in otherwise healthy young adults. Owing to the frequent occurrence of convulsive phenomena during the acute episode, syncope may be misdiagnosed and treated as epilepsy. Few works showed that during the interictal EEG recording of young adults with neurally mediated syncope, relevant EEG changes (such as "pseudoparoxysmal activity") may also be present, in particular during HV. The aim of this study is to evaluate the correlation between EEG and TCD (transcranial doppler) in patients with neurally-mediated syncope, compared with a group of healty controls, during hyperventilation. This study showed that patients with vasovagal syncope may be more sensitive to metabolic and blood pCO2 modifications induced by HV. Further studies like this one will clarify the extremely complex pathophysiology of neurally mediated syncope.